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8.55134

Ramage Amide AM resin

Novabiochem®

Synonym(s):

2-{[(R,S)-5-(9-Fluorenylmethyloxycarbonyl-amino)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene-2-yl]oxy}acetyl-AM resin

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Size/SKUAvailabilityPrice
5 g
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$437.00

About This Item

NACRES:
NA.22
UNSPSC Code:
12352111

$437.00


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Quality Segment

product line

Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

General description

Ramage Amide AM resin comprises Ramage′s dibenzocycloheptadienelinker [1] attached to aminomethylated polystyrene. Following Fmoc removal, the resin can be acylated under standard conditions and used in Fmoc SPPS. The linker is considerably more acid sensitive than the Rink amide or PAL linkers. This enables peptide amides to be released from the resin with 3% TFA in DCM and thus makes it a useful tool for the synthesis of acid sensitive peptides or protected peptide fragments.


Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

[1] R. Ramage, et al. (1993) Tetrahedron Lett., 34, 6599.

Analysis Note

Colour (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 0.80 mmol/g
Swelling Volume (in DMF): lot specific result

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
855001855130855008
description

Novabiochem®

description

Novabiochem®

description

Novabiochem®

description

Novabiochem®

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

functional group

amine

functional group

amine

functional group

amine

functional group

amine

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

Quality Level

200

Quality Level

400

Quality Level

400

Quality Level

400

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

form

beads

form

beads

form

powder

form

beads


Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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