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8.55134

Ramage Amide AM resin

Novabiochem®

Synonym(s):

2-{[(R,S)-5-(9-Fluorenylmethyloxycarbonyl-amino)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene-2-yl]oxy}acetyl-AM resin

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Pack SizeSKUAvailabilityPrice
5 g
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$437.00

About This Item

NACRES:
NA.22
UNSPSC Code:
12352111

$437.00


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Quality Level

product line

Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

General description

Ramage Amide AM resin comprises Ramage′s dibenzocycloheptadienelinker [1] attached to aminomethylated polystyrene. Following Fmoc removal, the resin can be acylated under standard conditions and used in Fmoc SPPS. The linker is considerably more acid sensitive than the Rink amide or PAL linkers. This enables peptide amides to be released from the resin with 3% TFA in DCM and thus makes it a useful tool for the synthesis of acid sensitive peptides or protected peptide fragments.


Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

[1] R. Ramage, et al. (1993) Tetrahedron Lett., 34, 6599.

Analysis Note

Colour (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 0.80 mmol/g
Swelling Volume (in DMF): lot specific result

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
8.550018.551308.55008
reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

functional group

amine

functional group

amine

functional group

amine

functional group

amine

Quality Level

200

Quality Level

400

Quality Level

400

Quality Level

400

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-8°C


Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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Protocols

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

Articles

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.





Global Trade Item Number

SKUGTIN
855134000504027269207557
855134000104027269207540
855134025004027269285692

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