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8.55157

MeDbz NovaSyn®TGR resin

Novabiochem®

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About This Item

NACRES:
NA.22
UNSPSC Code:
13111023
Pricing and availability is not currently available.
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Quality Level

product line

NovaSyn® TG, Novabiochem®

form

solid

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

General description

MeDbz NovaSyn TGR resin is a second generation Dbz resin that overcomes the problem of branched peptide formation of the original and provides a robust approach to the synthesis of peptide thioesters by Fmoc SPPS. This product is used exactly in the same manner as standard Dbz resins except that special conditions are not required for loading of the first amino acid. Peptide chain extension is performed on the 4-anilino group, followed by formation of an imidazolidinone (MeNbz) with p-nitrophenyl chloroformate, and cleavage from the resin with TFA. The peptide-MeNbz is used directly in chemical ligation reactions to generate in situ the desired peptide thioester.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Legal Information

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
8.550138.551558.55007
reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

functional group

amine

functional group

amine

functional group

amine

functional group

amine

product line

NovaSyn® TG, Novabiochem®

product line

NovaSyn® TG, Novabiochem®

product line

NovaSyn® TG, Novabiochem®

product line

NovaSyn® TG, Novabiochem®

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-30°C


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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Articles

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.





Global Trade Item Number

SKUGTIN
855157999904027269701093
855157002504027269701123
855157000504027269701109
855157000104027269701116

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