8.56041
Fmoc-Trp(Boc)-NovaSyn® TGA
Novabiochem®
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| Size/SKU | Availability | Price |
|---|---|---|
5 g | Check Cart for Availability | $644.00 |
About This Item
NACRES:
NA.22
UNSPSC Code:
12352209
Quality Segment
product line
NovaSyn® TG, Novabiochem®
form
beads
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
Boc, Fmoc
storage temp.
2-8°C
General description
Pre-loaded resin for synthesis of peptide acids containing a C-terminal tryptophan amino-acid residue by Fmoc SPPS.
The N-in-Boc group helps minimize reattachment of peptides during TFA-mediated cleavage. The base NovaSyn TG is a composite of low cross-linked polystyrene and 3000-4000 M.W. polyethylene glycol. Peptide synthesis occurs at the ends of the PEG chains which have been functionalized with a TFA-labile Wang-type linker. NovaSyn TG resins are ideal for the synthesis of difficult and long peptides as the PEG helps solvate the growing peptide chains and increase site isolation, thereby improving synthesis efficiency and peptide product quality. The 90 μm beads have a narrow size distribution, high diffusion rates and excellent swelling properties across a wide range of solvents from toluene to water, making them ideally suited to the synthesis of serial and parallel peptide
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
The N-in-Boc group helps minimize reattachment of peptides during TFA-mediated cleavage. The base NovaSyn TG is a composite of low cross-linked polystyrene and 3000-4000 M.W. polyethylene glycol. Peptide synthesis occurs at the ends of the PEG chains which have been functionalized with a TFA-labile Wang-type linker. NovaSyn TG resins are ideal for the synthesis of difficult and long peptides as the PEG helps solvate the growing peptide chains and increase site isolation, thereby improving synthesis efficiency and peptide product quality. The 90 μm beads have a narrow size distribution, high diffusion rates and excellent swelling properties across a wide range of solvents from toluene to water, making them ideally suited to the synthesis of serial and parallel peptide
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Analysis Note
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.10 - 0.30 mmol/g
Swelling Volume (in DMF): lot specific result
Identity (of the substitution): passes test
The base resin is PEG-PS-copolymer (90µm), functionalised with 4-hydroxy-methylphenoxyacetic acid.
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.10 - 0.30 mmol/g
Swelling Volume (in DMF): lot specific result
Identity (of the substitution): passes test
The base resin is PEG-PS-copolymer (90µm), functionalised with 4-hydroxy-methylphenoxyacetic acid.
Other Notes
Replaces: 04-12-2675
Legal Information
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
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This Item | |||
|---|---|---|---|
| description Novabiochem® | description Novabiochem® | description Novabiochem® | description Novabiochem® |
| form beads | form beads | form powder | form powder |
| functional group Boc, Fmoc | functional group Boc, Fmoc | functional group - | functional group Boc, Fmoc |
| product line NovaSyn® TG, Novabiochem® | product line Novabiochem® | product line Novabiochem® | product line Novabiochem® |
| storage temp. 2-8°C | storage temp. 2-30°C | storage temp. 15-25°C | storage temp. −20°C |
| Quality Level 200 | Quality Level 400 | Quality Level 200 | Quality Level 300 |
| reaction suitability reaction type: Fmoc solid-phase peptide synthesis | reaction suitability reaction type: Fmoc solid-phase peptide synthesis | reaction suitability reaction type: Boc solid-phase peptide synthesis | reaction suitability reaction type: Fmoc solid-phase peptide synthesis |
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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