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Anti-CD11b, (human/mouse), redFluor^® 710, clone M1/70 Antibody

Name: Anti-CD11b, (human/mouse), redFluor<SUP>®</SUP> 710, clone M1/70 Antibody
Brand: MM
Price: 200 USD
Availability: InStock

clone M1/70, from rat, redFluor^® 710

Synonym(s):

Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, CD11b, CD11b

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Size/SKU	Availability	Price
25 μg	Check Cart for Availability	$200.00
100 μg	Check Cart for Availability	$355.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

redFluor^® 710

Clone:

M1/70, monoclonal

Application:

FACS

Citations:

$200.00

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Properties

biological source

rat

Quality Segment

100

conjugate

redFluor^® 710

antibody form

purified antibody

antibody product type

primary antibodies

clone

M1/70, monoclonal

species reactivity

mouse, human

packaging

antibody small pack of 25 μg

technique(s)

flow cytometry: suitable

isotype

IgG2bκ

UniProt accession no.

P05555

target post-translational modification

unmodified

Description

General description

The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The M1/70 antibody is widely used as a marker for CD11b expression on mouse macrophages, granulocytes, neutrophils, and NK cells. The antibody is also reported to be cross-reactive for Rhesus macaque CD11b.

Immunogen

Immunogen information for this antibody is proprietary information.

Application

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

This rat monoclonal Anti-CD11b Antibody, (human/mouse), redFluor^® 710, clone M1/70, Cat. No. MABF804 is validated for use in Flow Cytometry, for the detection of CD11b.

Physical form

Purified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.

Purified by size-exclusion chromatography

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Analysis Note

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.25 μg from a representative lot detected CD11b in one million C57Bl/6 bone marrow cells.

Other Notes

Concentration: Please refer to lot specific datasheet.

Legal Information

redFluor is a registered trademark of Tonbo Biotechnologies

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	MABF80A	MABF366	MABF520
Sigma-Aldrich MABF80B Anti-CD11b, (human/mouse), redFluor^® 710, clone M1/70 Antibody	Sigma-Aldrich MABF80A Anti-CD11b, (human/mouse), FITC, clone M1/70 Antibody	Sigma-Aldrich MABF366 Anti-CD11b Antibody (human/mouse), APC, clone M1/70	Sigma-Aldrich MABF520 Anti-CD11b Antibody (human/mouse), APC, clone M1/70
description clone M1/70, from rat, redFluor^® 710	description clone M1/70, from rat, FITC conjugate	description clone M1/70, 0.2 mg/mL, from rat	description clone M1/70, 0.2 mg/mL, from rat
biological source rat	biological source rat	biological source rat	biological source rat
species reactivity mouse, human	species reactivity human, mouse	species reactivity mouse, human	species reactivity mouse, human
antibody form purified antibody	antibody form purified antibody	antibody form purified antibody	antibody form purified antibody
conjugate redFluor^® 710	conjugate FITC conjugate	conjugate Allophycocyanin conjugate	conjugate Allophycocyanin conjugate
clone M1/70, monoclonal	clone M1/70, monoclonal	clone M1/70, monoclonal	clone M1/70, monoclonal
technique(s) flow cytometry: suitable	technique(s) flow cytometry: suitable	technique(s) immunoprecipitation (IP): suitable, flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable	technique(s) flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable

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Storage Class

12 - Non Combustible Liquids

WGK

nwg

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