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07858

(R)-(−)-3-Amino-1-Boc-piperidine

≥98.0% (TLC)

Synonym(s):

(R)-1-Boc-3-piperidinamine, tert-Butyl (R)-3-amino-1-piperidinecarboxylate

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Size/SKUAvailabilityPrice
1 g
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$311.00

About This Item

Empirical Formula (Hill Notation):
C10H20N2O2
CAS Number:
Molecular Weight:
200.28
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:

$311.00


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Quality Segment

assay

≥98.0% (TLC)

optical activity

[α]/D -28.5±2°, c = 1 in DMF

SMILES string

CC(C)(C)OC(=O)N1CCC[C@@H](N)C1

InChI

1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1

InChI key

AKQXKEBCONUWCL-MRVPVSSYSA-N

General description

(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.

Application

(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.

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description

≥98.0% (TLC)

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description

≥98.0% (TLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

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optical activity

[α]/D -28.5±2°, c = 1 in DMF

optical activity

[α]22/D +3.2°, c = 0.5 in DMF

optical activity

-

optical activity

[α]/D +32.0±3°, c = 1 in DMF

assay

≥98.0% (TLC)

assay

97%

assay

97%

assay

≥98.0% (TLC)


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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