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09668

N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate

≥99.0% (TLC/N)

Synonym(s):

O-(N-Succinimidyl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate, HSTU

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Size/SKUAvailabilityPrice
5 g
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$116.00

About This Item

Empirical Formula (Hill Notation):
C9H16F6N3O3P
CAS Number:
Molecular Weight:
359.21
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352101
MDL number:

$116.00


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Quality Segment

assay

≥99.0% (TLC/N)

form

crystals

reaction suitability

reaction type: Coupling Reactions

mp

218-221 °C (dec.)

solubility

acetonitrile: 0.5 g/mL, slightly hazy, colorless

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

F[P-](F)(F)(F)(F)F.CN(C)C(\ON1C(=O)CCC1=O)=[N+](\C)C

InChI

1S/C9H16N3O3.F6P/c1-10(2)9(11(3)4)15-12-7(13)5-6-8(12)14;1-7(2,3,4,5)6/h5-6H2,1-4H3;/q+1;-1

InChI key

STWZCCVNXFLDDD-UHFFFAOYSA-N

General description

N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate can be used to prepare N-succinimidyl 4-[18F]fluorobenzoate ([18F]-SFB), a prosthetic group for the fluorination of biomolecules for PET imaging.

Application

Reactant for:
Synthesis of liposomal contrast agents for magnetic resonance imaging
Synthesis of thiol-reactive Cy5 derivatives
Synthesis of protein labeling molecules

Other Notes

Coupling reagent for peptide synthesis and the formation of other amides. Even in aqueous solution yields are excellent

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This Item
04936385530305308
description

≥99.0% (TLC/N)

description

≥98.0% (HPLC)

description

97%

description

85%

form

crystals

form

powder

form

-

form

-

storage temp.

−20°C

storage temp.

-

storage temp.

2-8°C

storage temp.

-

reaction suitability

reaction type: Coupling Reactions

reaction suitability

reaction type: Coupling Reactions

reaction suitability

reaction type: Coupling Reactions

reaction suitability

-

solubility

acetonitrile: 0.5 g/mL, slightly hazy, colorless

solubility

-

solubility

-

solubility

-

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

mp

218-221 °C (dec.)

mp

185-190 °C

mp

198-201 °C (lit.)

mp

239 °C (dec.) (lit.)


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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