14340
(+)-Bicuculline
≥97.0% (TLC), GABAA receptor antagonist, powder
Synonym(s):
Bucuculline
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
25 mg | Check Cart for Availability | $72.50 |
100 mg | Check Cart for Availability | $112.00 |
500 mg | Check Cart for Availability | $445.00 |
About This Item
$72.50
Product Name
(+)-Bicuculline, ≥97.0% (TLC)
Quality Segment
assay
≥97.0% (TLC)
form
powder
optical activity
[α]20/D +126±6°, c = 1% in chloroform
mp
193-197 °C
SMILES string
[H][C@]1(OC(=O)c2c3OCOc3ccc12)[C@@]4([H])N(C)CCc5cc6OCOc6cc45
InChI
1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1
InChI key
IYGYMKDQCDOMRE-ZWKOTPCHSA-N
Gene Information
rat ... Gabra2(29706)
General description
Application
- as a compound to compare pharmacodynamics and network activity profiles of conolidine/cannabidiol
- to study the effects of chronic caffeine administration on the function of GABAA receptor
- to isolate N-methyl-D-aspartate receptor (NMDAR)-specific evoked and miniature excitatory postsynaptic currents (eEPSCs and mEPSCs) in neurons of rats
Biochem/physiol Actions
Features and Benefits
1 of 1
This Item | |||
|---|---|---|---|
| description ≥97.0% (TLC) | description phyproof® Reference Substance | description ≥95.0% (HPCE) | description AldrichCPR |
| form powder | form - | form powder | form solid |
| assay ≥97.0% (TLC) | assay ≥98.0% (HPLC) | assay ≥95.0% (HPCE) | assay - |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level - |
| mp 193-197 °C | mp - | mp - | mp - |
| Gene Information rat ... Gabra2(29706) | Gene Information - | Gene Information - | Gene Information - |
| optical activity [α]20/D +126±6°, c = 1% in chloroform | optical activity - | optical activity [α]/D -117±7°, c = 1 in chloroform | optical activity - |
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Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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