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22632

Quinine hydrochloride dihydrate

tested according to Ph. Eur.

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Synonym(s):

Chinini hydrochloridum, (8α, 9R)-6′-Methoxycinchonan-9-ol monohydrochloride dihydrate

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Size/SKUAvailabilityPrice
50 g

Available to ship TODAYfromMILWAUKEE

$308.00

About This Item

Empirical Formula (Hill Notation):
C20H24N2O2 · HCl · 2H2O
CAS Number:
Molecular Weight:
396.91
UNSPSC Code:
12352210
NACRES:
NA.25
PubChem Substance ID:
EC Number:
205-001-1
Beilstein/REAXYS Number:
6112655
MDL number:
Form:
solid

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agency

tested according to Ph. Eur.

Quality Segment

form

solid

solubility

water: soluble 0.25 mg in 5 ml

application(s)

research use (small molecule)

SMILES string

O.O.Cl.COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1

InChI

1S/C20H24N2O2.ClH.2H2O/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H;2*1H2/t13-,14-,19-,20+;;;/m0.../s1

InChI key

MPQKYZPYCSTMEI-FLZPLBAKSA-N

Application

Quinine hydrochloride dehydrate has been used for fluorescent in situ detection of quinine in cinchona bark using UV resonance raman spectroscopy. It has also been used as a actinometric system to measure the light-induced changes in ruthenium anticancer agent, NAMI-A.

Biochem/physiol Actions

Quinine is a very effective anti-malarial treatment but is considered toxic for routine treatment due to the development of drug resistance in the malarial parasites. It acts as blood schizonticide.Quinine reportedly blocks the membrane conductance of potassium in enteric neurons.

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This Item
159680722630145920
description

tested according to Ph. Eur.

description

United States Pharmacopeia (USP) Reference Standard

description

BioReagent, suitable for fluorescence, ≥98.0% (NT)

description

90%

form

solid

form

-

form

powder

form

solid

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

solubility

water: soluble 0.25 mg in 5 ml

solubility

-

solubility

H2O: soluble

solubility

-

agency

tested according to Ph. Eur.

agency

USP

agency

-

agency

-

application(s)

research use (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-


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pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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Questions

1–2 of 2 Questions  
  1. What is the solubility of this product in ethanol ?

    1 answer
    1. The solubility of this product in ethanol has not been determined. However, it states that the chemical is soluble in ethanol.

      Helpful?

  2. Löslichkeit in Ethanol

    1 answer
    1. The solubility of this product in ethanol has not been determined. However, various sources state that the chemical is soluble in ethanol. See the link below for an example:
      https://www.ipcinfo.org/fileadmin/user_upload/jecfa_additives/docs/Monograph1/Additive-369.pdf

      Helpful?

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