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Voriconazole

Name: Voriconazole
Brand: SIAL
Price: 156 USD
Availability: InStock

VETRANAL^®, analytical standard

Synonym(s):

2R,3S-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, UK-109496

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Size/SKU	Availability	Price
25 mg	Check Cart for Availability	$156.00

About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₄F₃N₅O

CAS Number:

137234-62-9

Molecular Weight:

349.31

NACRES:

NA.24

PubChem Substance ID:

329754241

UNSPSC Code:

41116107

MDL number:

MFCD00905717

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Properties

grade

analytical standard

Quality Segment

100

product line

VETRANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

C[C@@H](c1ncncc1F)[C@](O)(Cn2cncn2)c3ccc(F)cc3F

InChI

1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1

InChI key

BCEHBSKCWLPMDN-MGPLVRAMSA-N

Description

General description

Voriconazole is a second-generation triazole, and is derived from fluconazole. It has a broad and enhanced antifungal spectrum as compared to other older triazoles. It is mostly well tolerated and is available in both oral and intravenous formulations.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

It has been used as one of the constituent of YPD (1% yeast extract, 2% peptone, 2% glucose) liquid media.

Voriconazole is an antifungal used to treat serious fungal infections. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-a sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes.

Voriconazole is an antifungal used to treat serious fungal infections. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes.

Voriconazole is an antifungal, which inhibits ergosterol synthesis.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item	Y0001395	1718008	1354251
Supelco 32483 Voriconazole	Y0001395 Voriconazole	USP 1718008 Voriconazole	USP 1354251 Itraconazole
description VETRANAL^®, analytical standard	description European Pharmacopoeia (EP) Reference Standard	description United States Pharmacopeia (USP) Reference Standard	description United States Pharmacopeia (USP) Reference Standard
grade analytical standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard
format neat	format neat	format neat	format neat
Quality Level 100	Quality Level -	Quality Level -	Quality Level -
shelf life limited shelf life, expiry date on the label	shelf life -	shelf life -	shelf life -
application(s) forensics and toxicology pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)
product line VETRANAL^®	product line -	product line -	product line -

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Pictograms

GHS06,GHS08

Signal Word

Danger

Hazard Codes

H301,H341,H351,H361,H371,H372,H373,H412

Precautionary Statements

P202 - P260 - P264 - P270 - P273 - P301 + P310

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 2 - Muta. 2 - Repr. 2 - STOT RE 1 - STOT RE 2 Oral - STOT SE 2 Oral

Target Organs

Eyes, Liver,Kidney

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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Certificates of Analysis (COA)

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