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436143

Sodium dodecyl sulfate

ACS reagent, ≥99.0%

Sustainability features

Synonym(s):

Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

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Size/SKUAvailabilityPrice
25 g
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$71.40
100 g
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$212.00

About This Item

Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
Molecular Weight:
288.38
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
39093306
UNSPSC Code:
12161900
EC Number:
205-788-1
MDL number:
Beilstein/REAXYS Number:
3599286

$71.40


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grade

ACS reagent

Quality Segment

assay

≥99.0%

form

solid

mol wt

288.38 g/mol

sustainability

Sustainability features

description

anionic, 62

impurities

≤0.06 meq/g Titr. Base, ≥96.0% fatty alcohols, <4.0% unsulfated alcohols

loss

≤1.0% loss on drying

mp

204-207 °C (lit.)

solubility

H2O: soluble 1 gm in 10 ml (opalescent solution)

density

1.03 g/cm3 at 20 °C

cation traces

heavy metals (as Pb): ≤0.002%

λ

3 %H2O reference

UV absorption

λ: 220-350 nm Amax: ≤0.1

HLB

40

greener alternative category

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

General description

This product aligns with one or more of the 12 Principles of Green ChemistryThis product is used as a surfactant to enhance catalysis.  Click here for more information.
Sodium dodecyl sulfate (SDS), also known as sodium lauryl sulfate, is a versatile anionic surfactant with a broad range of applications in cell biology, biochemistry, and various industries. Its amphiphilic nature, characterized by a hydrophobic hydrocarbon tail and a hydrophilic sulfate head group, makes it an effective detergent capable of solubilizing and denaturing proteins, lipids, and other hydrophobic molecules.

In protein biochemistry, SDS plays a pivotal role in protein extraction and SDS-PAGE (sodium dodecyl sulfate-polyacrylamide gel electrophoresis). Its ability to denature proteins by disrupting their secondary and tertiary structures allows for their uniform migration through a polyacrylamide gel matrix based on their molecular weight. This technique, SDS-PAGE, has become an indispensable tool for analyzing protein size and purity.

Beyond protein analysis, SDS also finds applications in nucleic acid extraction and hybridization techniques. Its detergent properties aid in the lysis of cells and the solubilization of cellular components, facilitating the extraction of DNA and RNA. This makes SDS a valuable reagent in various molecular biology protocols, including PCR (polymerase chain reaction) and Southern blotting. Sodium dodecyl sulfate stands as a versatile and widely used surfactant with a diverse range of applications due to its ability to solubilize, denature, and separate biological molecules for cell biology and biochemical research.

Application

Anionic detergent
Sodium dodecyl sulfate was used as a test compound for studying that whether Bacillus amyloliquefaciens KPS46 can induce priming, signaling, protein production as well as systemic protection in soybean (Glycine max L.) against several diseases.

Biochem/physiol Actions

Sodium dodecyl sulfate (SDS) is an anionic detergent that can form complexes with protein through hydrophobic interactions. Studies have reported that the hydrodynamic functions of protein-SDS complexes are governed by the length of their polypeptide chains. Thus, SDS-based electrophoretic techniques can separate protein molecules based on their molecular weights. Additionally, SDS can solubilize cell membranes and can extract membrane-bound proteins.

Features and Benefits

  • Highly versatile surfactant for your molecular biology and biochemical research
  • Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

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This Item
6286242802375746
description

ACS reagent, ≥99.0%

description

≥90% ((Assay))

description

Molecular Biology Grade

description

≥99.0% (GC), dust-free pellets

assay

≥99.0%

assay

≥90% ((Assay))

assay

≥99%

assay

≥99.0% (GC)

form

solid

form

(Rods)

form

solid

form

rod

grade

ACS reagent

grade

-

grade

Molecular Biology

grade

-

mol wt

288.38 g/mol

mol wt

288.38 g/mol

mol wt

-

mol wt

average mol wt 18,000

HLB

40

HLB

40

HLB

-

HLB

40(lit.)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200


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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

4.1B - Flammable solid hazardous materials

WGK

WGK 2

Flash Point (°F)

338.0 °F

Flash Point (°C)

170 °C

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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