Potency is not tested for this product.
45656
Rotenone
PESTANAL®, analytical standard
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 250 mg | Estimated to ship TODAYfromMilwaukee Teutonia Distributio | $73.50 |
About This Item
Empirical Formula (Hill Notation):
C23H22O6
CAS Number:
Molecular Weight:
394.42
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
201-501-9
Beilstein/REAXYS Number:
6773081
MDL number:
grade
analytical standard
Quality Level
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
bp
210-220 °C/0.5 mmHg (lit.)
mp
159-164 °C (lit.)
application(s)
agriculture
environmental
format
neat
SMILES string
COc1cc2OCC3Oc4c5C[C@@H](Oc5ccc4C(=O)C3c2cc1OC)C(C)=C
InChI
1S/C23H22O6/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14/h5-7,9,16,20-21H,1,8,10H2,2-4H3/t16-,20-,21+/m1/s1
InChI key
JUVIOZPCNVVQFO-HBGVWJBISA-N
General description
Rotenone is a contact insecticide and a slow stomach poison, extremely potent against many insects. It is widely used against Varroa Jacobsoni mite, affecting colonies of honey bees.
Application
Rotenone may be used as an analytical reference standard for the quantification of the analyte in raw honey samples and biological samples using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Inhibitor of mitochondrial electron transport.
Rotenone is an inhibitor of mitochondrial electron transport at nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone acts as a neurotoxic agent which can produce Parkinson-like condition to serve as an animal model for the study of etiology and interventions. The primary mechanism of action of rotenone is complex I inhibition, followed by the generation of oxidative stress and oxidative damage. Because rotenone is lipophilic, it readily penetrates the brain, where it attaches to and inhibits mitochondrial complex I of electron chain transport (ETC).
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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This Item | |||
|---|---|---|---|
| format neat | format - | format - | format - |
| technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) - | technique(s) - | technique(s) - |
| grade analytical standard | grade certified reference material, TraceCERT® | grade - | grade - |
| product line PESTANAL® | product line TraceCERT® | product line - | product line - |
| bp 210-220 °C/0.5 mmHg (lit.) | bp 210-220 °C/0.5 mmHg (lit.) | bp 210-220 °C/0.5 mmHg (lit.) | bp - |
| application(s) agriculture | application(s) - | application(s) - | application(s) - |
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Danger
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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Botanical Pesticides in Agriculture, 983(1-2), 43-50 (1996)
Determination of rotenone in river water utilizing packed capillary column switching liquid chromatography with UV and time-of-flight mass spectrometric detection
Holm A, et al.
Journal of Chromatography A, 983(1-2), 43-50 (2003)
Jun Matsumoto et al.
Antimicrobial agents and chemotherapy, 52(1), 164-170 (2007-10-24)
Alveolar echinococcosis, which is due to the massive growth of larval Echinococcus multilocularis, is a life-threatening parasitic zoonosis distributed widely across the northern hemisphere. Commercially available chemotherapeutic compounds have parasitostatic but not parasitocidal effects. Parasitic organisms use various energy metabolic
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 45656-250MG | 04061832341545 |
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