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63175

4-Maleimidobutyric acid N-hydroxysuccinimide ester

≥98.0% (HPLC)

Synonym(s):

4-Maleimidobutyric acid N-succinimidyl ester, N-(γ-Maleimidobutyryloxy)succinimide, N-Succinimidyl 4-maleimidobutyrate, GMBS

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Size/SKUAvailabilityPrice
100 mg
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$397.00

About This Item

Empirical Formula (Hill Notation):
C12H12N2O6
CAS Number:
Molecular Weight:
280.23
UNSPSC Code:
12352106
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6427689
Assay:
≥98.0% (HPLC)

$397.00


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Quality Segment

assay

≥98.0% (HPLC)

reaction suitability

reagent type: linker

technique(s)

targeted protein degradation: suitable

mp

123-129 °C

functional group

NHS ester

storage temp.

2-8°C

SMILES string

O=C1N(CCCC(ON2C(CCC2=O)=O)=O)C(C=C1)=O

InChI

1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2

InChI key

PVGATNRYUYNBHO-UHFFFAOYSA-N

Application

A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 7-atom linker.

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This Item
568600M552556189
description

≥98.0% (HPLC)

description

98%

description

≥98%, powder

description

BioReagent, suitable for fluorescence, ≥97% (C)

assay

≥98.0% (HPLC)

assay

98%

assay

≥98%

assay

≥97% (C)

reaction suitability

reagent type: linker

reaction suitability

reagent type: cross-linking reagent

reaction suitability

reagent type: linker

reaction suitability

-

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

mp

123-129 °C

mp

70-73 °C (lit.)

mp

180-182 °C (lit.)

mp

132-133 °C (lit.)

functional group

NHS ester

functional group

maleimide, NHS ester

functional group

NHS ester

functional group

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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