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69479

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

derivatization grade (GC derivatization), LiChropur™, ≥98.5%

Synonym(s):

N-Trimethylsilyl-N-methyl trifluoroacetamide, MSTFA

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Size/SKUAvailabilityPrice
5 mL

Available to ship TODAYfromMILWAUKEE

$135.00
$114.75
10 x 1 mL

Available to ship TODAYfromMILWAUKEE

$217.00
25 mL

Available to ship TODAYfromMILWAUKEE

$403.00

About This Item

Linear Formula:
CF3CON(CH3)Si(CH3)3
CAS Number:
Molecular Weight:
199.25
UNSPSC Code:
23151817
NACRES:
NA.22
PubChem Substance ID:
EC Number:
246-331-6
Beilstein/REAXYS Number:
1941550
MDL number:
Assay:
≥98.5% (GC), ≥98.5%
Form:
liquid

$114.75

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grade

derivatization grade (GC derivatization)

Quality Segment

vapor density

>1 (vs air)

vapor pressure

8.8 mmHg ( 27 °C)

assay

≥98.5% (GC), ≥98.5%

form

liquid

quality

LiChropur™

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.38 (lit.), n20/D 1.380

bp

130-132 °C (lit.)

density

1.075 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CN(C(=O)C(F)(F)F)[Si](C)(C)C

InChI

1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3

InChI key

MSPCIZMDDUQPGJ-UHFFFAOYSA-N

General description

N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a silylating reagent.

Application

MSTFA may be used in silylation procedure to detemine steroid hormones 17α-ethinylestradiol (EE2) and estrone using GC-MS. MSTFA along with Trimethylsilyl chloride (TMCS) in eithyl acetate, acetonitrile and dichloromethane solvents leads to formation of trimethylsilyl (TMS) and tert-butyldimethylsilyl (TBS) derivatives.
Learn more in the Product Information
Suitable for the derivatization of amines, amino acids, carboxyl, hydroxyamines, indolalkylamine, n-nitrosoamino acids, nucleosides, phenolalkylamines, serotonin and tryptamine.

Other Notes

Powerful silylating agent
Reagent for N-acetyl-N, trifluoroacetyl, trimethylsilyl, N-trimethylsilyl-N-trifluoroacetyl, and O-trimethylsilyl (TMS)

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

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M789139486612124
description

derivatization grade (GC derivatization), LiChropur™, ≥98.5%

description

BioReagent, for silylations, LiChropur™

description

synthesis grade

description

derivatization grade (GC derivatization), LiChropur™, activated with imidazole

assay

≥98.5% (GC)

assay

-

assay

≥98%

assay

-

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

reaction type: Silylations, reagent type: derivatization reagent

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

refractive index

n20/D 1.38 (lit.), n20/D 1.380

refractive index

n20/D 1.38 (lit.)

refractive index

n20/D 1.38 (lit.)

refractive index

n20/D 1.383

bp

130-132 °C (lit.)

bp

130-132 °C (lit.)

bp

130-132 °C (lit.)

bp

-

form

liquid

form

liquid

form

liquid

form

-


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Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

3 - Flammable liquids

WGK

WGK 3

Flash Point (°F)

77.0 °F - closed cup

Flash Point (°C)

25 °C - closed cup

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What is the packaging of the product N-Methyl-N-(trimethylsilyl)trifluoroacetamide, code: 69479-10X1ML, bottle, ampoule, blister or other??

    1 answer
    1. The 1ML size is packaged in a 5mL amber glass vial with a Schwarz-type septum cap. The vials are then placed in a 10-place overpack box with dividers to protect each vial. Please see the image below of this cap type.

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