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78246

Curcumin

suitable for matrix substance for MALDI-MS, ≥99.5% (HPLC)

Synonym(s):

(E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane, Diferulylmethane, Natural Yellow 3

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Size/SKUAvailabilityPrice
100 mg

Available to ship TODAY

$337.00

About This Item

Linear Formula:
[HOC6H3(OCH3)CH=CHCO]2CH2
CAS Number:
458-37-7
Molecular Weight:
368.38
EC Number:
207-280-5
UNSPSC Code:
41115710
NACRES:
NA.21
PubChem Substance ID:
329768129
MDL number:
MFCD00008365
Colour Index Number:
75300
Beilstein/REAXYS Number:
2306965
Assay:
≥99.5% (HPLC)
Form:
powder

$337.00

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vapor density

13 (vs air)

Quality Segment

assay

≥99.5% (HPLC)

form

powder

technique(s)

MALDI-MS: suitable

mp

183-188 °C

cation traces

Na: ≤50 mg/kg

suitability

suitable for matrix substance for MALDI-MS

storage temp.

2-8°C

SMILES string

COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O

InChI

1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+

InChI key

VFLDPWHFBUODDF-FCXRPNKRSA-N

Application


  • Hybrid Ethylcellulose Polymeric Films: Ag(I)-Based Components and Curcumin as Reinforcing Ingredients for Enhanced Food Packaging Properties: This research discusses the development of hybrid ethylcellulose films integrating curcumin to improve food packaging, emphasizing the analytical chemistry aspects like ingredient compatibility and performance evaluation (Crispini A et al., 2024).

  • Intelligent double-layer film based on gellan gum/modified anthocyanin/curcumin/sodium alginate/zinc oxide for monitoring shrimp freshness: This article describes the creation of an intelligent film incorporating curcumin for real-time monitoring of shrimp freshness, showcasing a practical application of curcumin in food safety and shelf-life extension (Li C et al., 2024).

  • Cyclodextrin-grafted redox-responsive hydrogel mediated by disulfide bridges for regulated drug delivery: This study examines a curcumin-incorporated cyclodextrin hydrogel, highlighting the use of curcumin in developing advanced drug delivery systems with potential applications in targeted therapy (Xu X et al., 2024).

Biochem/physiol Actions

A natural phenolic compound responsible for the yellow color of turmeric. Potent anti-tumor agent that acts against highly diverse tumor-specific pathways. Anti-inflammatory and anti-oxidant. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cyclooxygenase (COX-2) and 5-lipoxygenase (5-LOX).
A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.

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This Item
115185500280590PHL89180
Curcumin suitable for matrix substance for MALDI-MS, ≥99.5% (HPLC)

Supelco

78246

Curcumin

Curcumin United States Pharmacopeia (USP) Reference Standard

USP

1151855

Curcumin

Curcumin primary reference standard

00280590

Curcumin

Curcumin phyproof® Reference Substance

PHL89180

Curcumin

description

suitable for matrix substance for MALDI-MS, ≥99.5% (HPLC)

description

United States Pharmacopeia (USP) Reference Standard

description

primary reference standard

description

phyproof® Reference Substance

assay

≥99.5% (HPLC)

assay

-

assay

-

assay

≥98.0% (HPLC)

form

powder

form

-

form

powder or crystals

form

powder

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

-

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

mp

183-188 °C

mp

-

mp

-

mp

-

suitability

suitable for matrix substance for MALDI-MS

suitability

-

suitability

-

suitability

-

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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