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89802

4-(Dimethylamino)azobenzene-4′-sulfonyl chloride

derivatization grade (HPLC), LiChropur™, 98.0-102.0% (AT)

Synonym(s):

4-(4-Dimethylaminophenylazo)benzenesulfonyl chloride, DABS-Cl, Dabsyl chloride

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Size/SKUAvailabilityPrice
500 mg

Available to ship TODAYfromMILWAUKEE

$184.00

About This Item

Linear Formula:
(CH3)2NC6H4N=NC6H4SO2Cl
CAS Number:
Molecular Weight:
323.80
EC Number:
260-235-1
UNSPSC Code:
12352200
NACRES:
NA.22
Beilstein/REAXYS Number:
3064095
MDL number:

$184.00


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grade

derivatization grade (HPLC)

Quality Segment

assay

98.0-102.0% (AT)

form

crystals

quality

LiChropur™

technique(s)

HPLC: suitable, LC/MS: suitable, ion chromatography: suitable

mp

185 °C (dec.) (lit.)

SMILES string

CN(C)c1ccc(cc1)\N=N\c2ccc(cc2)S(Cl)(=O)=O

InChI

1S/C14H14ClN3O2S/c1-18(2)13-7-3-11(4-8-13)16-17-12-5-9-14(10-6-12)21(15,19)20/h3-10H,1-2H3/b17-16+

InChI key

VTVWTPGLLAELLI-WUKNDPDISA-N

General description

Amino groups are common to many biological compounds and many amines used in pharmaceuticals. Most of these compounds show weak absorption in direct HPLC analysis with UV-VIS detection. However, strongly absorbing derivatives of amines can be easily detected by HPLC with high sensitivity even when present at low concentrations. Primary and secondary amino groups are usually derivatized as aromatic derivatives by nucleophilic substitution reactions using reagents such as arylsulfonyl chlorides.
4-(Dimethylamino)azobenzene-4′-sulfonyl chloride, a well-known UV-labeling agent, is generally used for the derivatization of N-terminal amino acids, imidazole derivatives, polyamines, etc. prior to their chromatographic determination due to the former′s capacity to covalently bind to the substrates. Its derivatives typically absorb UV radiation between the range of 436-460 nm. This method of derivatization is regarded as superior compared to other methods owing to the simplicity of the procedure, high stability and reproducibility, best resolution of the analytes, etc.

Application

4-(Dimethylamino)azobenzene-4′-sulfonyl chloride may be used to derivatize biogenic amines, primary amino acids, melamine, and hydroxyproline and proline extracted from various biological samples prior to their determination using high performance liquid chromatography (HPLC) technique to increase their detection sensitivity.

Other Notes

Discover LiChropur™ reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

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This Item
39068669474
description

derivatization grade (HPLC), LiChropur™, 98.0-102.0% (AT)

description

≥97.5% (AT)

description

97%

mp

185 °C (dec.) (lit.)

mp

185 °C (dec.) (lit.)

mp

48-55 °C

form

crystals

form

-

form

solid

quality

LiChropur™

quality

-

quality

-

assay

98.0-102.0% (AT)

assay

≥97.5% (AT)

assay

97%

grade

derivatization grade (HPLC)

grade

-

grade

-

Quality Level

100

Quality Level

200

Quality Level

100


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Pictograms

Corrosion

Signal Word

Danger

Hazard Codes

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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