916641
2-(3-(Piperidin-4-yl)phenyl)ethan-1-amine dihydrochloride
95%
Synonym(s):
Semi-flexible linker for PROTAC® development
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Size/SKU | Availability | Price |
|---|---|---|
100 mg | Available to ship TODAYfromMILWAUKEE | $507.00 |
About This Item
Empirical Formula (Hill Notation):
C13H22Cl2N2
Molecular Weight:
277.23
MDL number:
UNSPSC Code:
12352116
NACRES:
NA.22
Assay:
95%
Form:
powder
Quality Segment
assay
95%
form
powder
reaction suitability
reagent type: linker
functional group
amine
storage temp.
2-8°C
SMILES string
NCCC1=CC=CC(C2CCNCC2)=C1.Cl.Cl
InChI key
ZFXFMAUVGRWYEM-UHFFFAOYSA-N
Application
2-(3-(Piperidin-4-yl)phenyl)ethan-1-amine dihydrochloride is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties.
Other Notes
Legal Information
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
1 of 1
This Item | |||
|---|---|---|---|
| description 95% | description - | description - | description ≥95% |
| assay 95% | assay - | assay - | assay ≥95% |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| form powder | form powder | form powder | form powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| functional group amine | functional group amine | functional group amine | functional group carboxylic acid |
| reaction suitability reagent type: linker | reaction suitability reagent type: linker | reaction suitability reagent type: linker | reaction suitability reagent type: linker |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.