This Ampicillin product is the Trihydrate form, CAS number 7177-48-2. This form is only soluble at 10 mg/mL in water. For higher solubility rates, the material may be prepared at 50 mg/mL in 1M Hydrochloric acid (HCl). Prepared solutions in HCl may then be diluted with medium or buffer. Please see the link below, under product A6140 Ampicillin Trihydrate, to review additional details:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/172/950/a6140pis.pdf
A1593
Ampicillin
meets USP testing specifications
Synonym(s):
Ampicillin trihydrate, D-(−)-α-Aminobenzylpenicillin
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| Size/SKU | Availability | Price |
|---|---|---|
25 g | Available to ship TODAYfromMILWAUKEE | $224.00 |
About This Item
Empirical Formula (Hill Notation):
C16H19N3O4S · 3H2O
CAS Number:
Molecular Weight:
403.45
UNSPSC Code:
51281703
NACRES:
NA.76
PubChem Substance ID:
EC Number:
200-709-7
Beilstein/REAXYS Number:
5399534
MDL number:
Quality Segment
agency
USP/NF, meets USP testing specifications
form
solid
color
white
mp
198-200 °C (dec.) (lit.)
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
application(s)
pharmaceutical (small molecule)
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O
InChI
1S/C16H19N3O4S.3H2O/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;;;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);3*1H2/t9-,10-,11+,14-;;;/m1.../s1
InChI key
RXDALBZNGVATNY-CWLIKTDRSA-N
General description
Chemical structure: β-lactam
Application
Used to select for ampicillin resistance in mutated and transformed cells.
Biochem/physiol Actions
A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Packaging
25g
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
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This Item | |||
|---|---|---|---|
| description meets USP testing specifications | description Pharmaceutical Secondary Standard; Certified Reference Material | description 900-1050 μg/mg anhydrous basis (HPLC) | description European Pharmacopoeia (EP) Reference Standard |
| mode of action cell wall synthesis | interferes | mode of action - | mode of action cell wall synthesis | interferes | mode of action - |
| antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum - | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum - |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level - |
| application(s) pharmaceutical (small molecule) | application(s) pharmaceutical (small molecule) | application(s) - | application(s) pharmaceutical (small molecule) |
| form solid | form - | form powder or crystals | form - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
Signal Word
Danger
Hazard Codes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
Storage Class
11 - Combustible Solids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Precautionary Statements
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How i can dissolve this into water? I tried to dissolve 2.5gm into 50 ml , but still not dissolved properly in water/
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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