Skip to Content
MilliporeSigma

Skip To

C7731

Caffeine

meets USP testing specifications, anhydrous

Synonym(s):

1,3,7-Trimethylxanthine

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
250 g

Available to ship onAugust 26, 2026fromMILWAUKEE

$140.00
1 kg

Available to ship onAugust 26, 2026fromMILWAUKEE

$469.00

About This Item

Linear Formula:
CH3(CH3)C6H4N4O2
CAS Number:
Molecular Weight:
194.19
UNSPSC Code:
12352210
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-362-1
Beilstein/REAXYS Number:
17705
MDL number:
Grade:
anhydrous
Agency:
USP/NF, meets USP testing specifications

$140.00


Available to ship onAugust 26, 2026Details


Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


grade

anhydrous

Quality Segment

agency

USP/NF, meets USP testing specifications

form

crystalline, powder

mp

234-236.5 °C (lit.)

solubility

H2O: soluble 18.7 g/L at 16 °C

SMILES string

CN1C(=O)N(C)c2ncn(C)c2C1=O

InChI

1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3

InChI key

RYYVLZVUVIJVGH-UHFFFAOYSA-N

General description

Caffeine is a commonly consumed pharmacologically active substance. It is a member of the class of methylxanthines. It is a natural alkaloid found in coffee, cocoa and other plants. Caffeine might be linked to osteoporosis, cardiovascular risk, arrhythmia and gastrointestinal disturbances. Caffeine is used to treat orthostatic hypotension, bronchopulmonary dysplasia and apnea of prematurity (AOP).

Application

Caffeine has been used:
  • to functionally disable Ca2+ removal via sarco/endoplasmic reticulum Ca2+ ATPase (SERCA)
  • to determine its effects in overcoming excitation-contraction-coupling failure
  • to compare its role as a stimulant with guarana


Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
27602W222402C0750
description

meets USP testing specifications, anhydrous

description

anhydrous, tested according to Ph. Eur.

description

anhydrous, 99%, FCC, FG

description

powder, ReagentPlus®

grade

anhydrous

grade

anhydrous

grade

Kosher, FG, Halal, anhydrous

grade

-

agency

USP/NF, meets USP testing specifications

agency

tested according to Ph. Eur.

agency

-

agency

-

mp

234-236.5 °C (lit.)

mp

234-236.5 °C (lit.)

mp

234-236.5 °C (lit.)

mp

234-236.5 °C (lit.)

Quality Level

200

Quality Level

100

Quality Level

400, 300

Quality Level

200

solubility

H2O: soluble 18.7 g/L at 16 °C

solubility

H2O: soluble 18.7 g/L at 16 °C

solubility

H2O: soluble 18.7 g/L at 16 °C

solubility

H2O: 15 mg/mL

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140), PDE4B(5142)
mouse ... Adora2b(11541)
rat ... Adora1(29290), Adora2a(25369)

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140), PDE4B(5142)
mouse ... Adora2b(11541)
rat ... Adora1(29290), Adora2a(25369)

Gene Information

human ... ADORA1(134), ADORA2B(136), ADORA3(140), PDE4B(5142)
mouse ... Adora2b(11541)
rat ... Adora1(29290), Adora2a(25369)

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140), PDE4B(5142), PRKAR1A(5573), PRKAR1AP(5574), PRKAR1B(5575), PRKAR2A(5576), PRKAR2B(5577)
mouse ... Adora2b(11541)
rat ... Adora1(29290), Adora2a(25369)


Still not finding the right product?

Explore all of our products under Caffeine


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Storage Class

11 - Combustible Solids



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Questions

Reviews

No rating value

Active Filters