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D0700000

Dexamethasone

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F

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Size/SKUAvailabilityPrice
70 mg

Available to ship TODAYfromMILWAUKEE

$188.00

About This Item

Empirical Formula (Hill Notation):
C22H29FO5
CAS Number:
Molecular Weight:
392.46
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-003-9
Beilstein/REAXYS Number:
2066651
MDL number:

$188.00


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biological source

synthetic

grade

pharmaceutical primary standard

API family

dexamethasone

packaging

pkg of 50 mg

manufacturer/tradename

EDQM

storage condition

protect from light

mp

262-264 °C (lit.)

solubility

water: <0.1 g/L

application(s)

pharmaceutical
pharmaceutical (small molecule)

format

neat

shipped in

ambient

SMILES string

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

InChI

1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

InChI key

UREBDLICKHMUKA-CXSFZGCWSA-N

Gene Information

human ... NR3C1(2908)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexamethasone EP reference standard may be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations, and biological samples by various analytical techniques.

Biochem/physiol Actions

Glucocorticoid anti-inflammatory agent
Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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This Item
PHR1526117600746165
description

European Pharmacopoeia (EP) Reference Standard

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

United States Pharmacopeia (USP) Reference Standard

description

VETRANAL®, analytical standard

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

USP

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

pharmaceutical secondary standard, certified reference material

grade

pharmaceutical primary standard

grade

analytical standard

format

neat

format

neat

format

neat

format

neat

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

clinical

solubility

water: <0.1 g/L

solubility

DMSO: soluble, methanol: sparingly soluble, water: practically insoluble, chloroform: slightly soluble, ether: very slightly soluble, acetone: sparingly soluble, dioxane: soluble

solubility

chloroform: slightly soluble, ethanol: sparingly soluble, acetone: sparingly soluble, water: practically insoluble, ether: very slightly soluble, methanol: sparingly soluble

solubility

-

API family

dexamethasone

API family

dexamethasone

API family

dexamethasone

API family

-


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Pictograms

Health hazard

Signal Word

Danger

Hazard Codes

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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