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D1000000

Dibenzosuberone

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

5-Dibenzosuberone, 10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-one, Dibenzocycloheptadienone

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Pack SizeSKUAvailabilityPrice
30 mg

Estimated to ship onJune 04, 2026fromMILWAUKEE

$154.00

About This Item

Empirical Formula (Hill Notation):
C15H12O
CAS Number:
1210-35-1
Molecular Weight:
208.26
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329798658
MDL number:
MFCD00003587
Beilstein/REAXYS Number:
1454355

$154.00

Estimated to ship onJune 04, 2026Details

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grade

pharmaceutical primary standard

API family

nortriptyline, amitriptyline

manufacturer/tradename

EDQM

refractive index

n20/D 1.6332 (lit.)

bp

148 °C/0.3 mmHg (lit.)

mp

32-34 °C (lit.)

density

1.156 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O=C1c2ccccc2CCc3ccccc13

InChI

1S/C15H12O/c16-15-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)15/h1-8H,9-10H2

InChI key

BMVWCPGVLSILMU-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dibenzosuberone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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This Item
BP858PHR28368.03559
Dibenzosuberone European Pharmacopoeia (EP) Reference Standard

D1000000

Dibenzosuberone

Dibenzosuberone British Pharmacopoeia (BP) Reference Standard

BP858

Dibenzosuberone

Amitriptyline Related Compound A certified reference material, pharmaceutical secondary standard

Supelco

PHR2836

Amitriptyline Related Compound A

Dibenzosuberone for synthesis

Sigma-Aldrich

8.03559

Dibenzosuberone

manufacturer/tradename

EDQM

manufacturer/tradename

BP

manufacturer/tradename

-

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical
pharmaceutical small molecule

application(s)

pharmaceutical small molecule

application(s)

-

format

neat

format

neat

format

-

format

-

refractive index

n20/D 1.6332 (lit.)

refractive index

n20/D 1.6332 (lit.)

refractive index

-

refractive index

-

density

1.156 g/mL at 25 °C (lit.)

density

1.156 g/mL at 25 °C (lit.)

density

-

density

1.16 g/cm3 at 25 °C

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

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Certificates of Analysis (COA)

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Solveigh C Koeberle et al.
Journal of medicinal chemistry, 55(12), 5868-5877 (2012-06-09)
Synthesis, biological testing, structure-activity relationships (SARs), and selectivity of novel disubstituted dibenzosuberone derivatives as p38 MAP kinase inhibitors are described. Hydrophilic moieties were introduced at the 7-, 8-, and 9-position of the 2-phenylamino-dibenzosuberones, improving physicochemical properties as well as potency.
S P Dixon et al.
Pharmeuropa scientific notes, 2005(1), 15-20 (2007-08-11)
An isocratic reversed-phase liquid chromatographic method is described using a hybrid column for the control of synthetic impurities potentially found in amitriptyline hydrochloride. The method has been validated and is capable of controlling impurities to 0.1 per cent.
Stefan Fischer et al.
Journal of medicinal chemistry, 56(1), 241-253 (2012-12-29)
p38α mitogen-activated protein (MAP) kinase is a main target in drug research concerning inflammatory diseases. Nevertheless, no inhibitor of p38α MAP kinase has been introduced to the market. This might be attributed to the fact that there is no inhibitor
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Global Trade Item Number

SKUGTIN
D100000004061833792827