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Ethylenediaminetetraacetic acid disodium salt dihydrate

Name: Ethylenediaminetetraacetic acid disodium salt dihydrate
Brand: SIAL

reagent grade, 98.5-101.5% (titration)

Synonym(s):

Disodium ethylenediaminetetraacetate dihydrate, EDTA disodium salt, EDTA-Na₂, Edathamil, Edetate disodium salt dihydrate, Sequestrene Na₂

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₄N₂Na₂O₈ · 2H₂O

CAS Number:

6381-92-6

Molecular Weight:

372.24

NACRES:

NA.77

PubChem Substance ID:

24894708

UNSPSC Code:

12352107

EC Number:

205-358-3

Beilstein/REAXYS Number:

3900609

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Properties

biological source

synthetic (organic)

Quality Segment

200

grade

reagent grade

agency

suitable for SM 4500 - NH3

assay

98.5-101.5% (titration)

form

powder

reaction suitability

reagent type: chelator

mp

248 °C (dec.) (lit.)

solubility

H₂O: soluble, clear, colorless

application(s)

agriculture
clinical research

storage temp.

room temp

SMILES string

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

InChI key

OVBJJZOQPCKUOR-UHFFFAOYSA-L

Description

General description

Ethylenediaminetetraacetic acid (EDTA) disodium salt is an aminopolycarboxylic acid and a hexadentate ligand. It chelates metal cations to form a stable octahedral complex. It is commonly added to buffers, solutions, and even soil samples to control the concentrations of metal ions or to remove metal contaminants. Metal chelators play a crucial role in various research applications, such as biochemistry, molecular biology, and analytical chemistry. For example, EDTA is a blood anticoagulant that chelates calcium ions in the blood, this inhibits clots and is routinely used in hematological assays.

Application

Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

Ethylenediaminetetraacetic acid disodium salt dihydrate has been used as a component of the plasma membrane resuspension buffer, inhibitor′s preservative solution (IS) and luciferase activity assay mix.

Features and Benefits

Reagent grade for general lab use

Other Notes

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This Item	E4884	E5134	E6635
Sigma-Aldrich ED2SS Ethylenediaminetetraacetic acid disodium salt dihydrate	Sigma-Aldrich E4884 Ethylenediaminetetraacetic acid disodium salt dihydrate	Sigma-Aldrich E5134 Ethylenediaminetetraacetic acid disodium salt dihydrate	Sigma-Aldrich E6635 Ethylenediaminetetraacetic acid disodium salt dihydrate
description reagent grade, 98.5-101.5% (titration)	description ACS reagent, 99.0-101.0%	description suitable for electrophoresis, Molecular Biology, 99.0-101.0% (titration)	description Sigma Grade, suitable for plant cell culture, 98.5-101.5%
grade reagent grade	grade ACS reagent	grade Molecular Biology	grade Sigma Grade
assay 98.5-101.5% (titration)	assay 99.0-101.0%	assay 99.0-101.0% (titration)	assay 98.5-101.5%
Quality Level 200	Quality Level 200	Quality Level 300	Quality Level 200
application(s) agriculture clinical research	application(s) microbiology	application(s) -	application(s) -
solubility H₂O: soluble, clear, colorless	solubility H₂O: 100 g/L at 20 °C	solubility 3 M NaOH: 1.6 g/10 mL	solubility H₂O: soluble, clear, colorless
mp 248 °C (dec.) (lit.)	mp 248 °C (dec.) (lit.)	mp 248 °C (dec.) (lit.)	mp 248 °C (dec.) (lit.)

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pictograms

GHS08,GHS07

signalword

Warning

hcodes

H332,H373

pcodes

P260 - P271 - P304 + P340 + P312 - P314 - P501

Hazard Classifications

Acute Tox. 4 Inhalation - STOT RE 2 Inhalation

target_organs

Respiratory Tract

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c