Key Documents

View All Documentation

Niacin (Nicotinic Acid)

Name: Niacin (Nicotinic Acid)
Brand: SIAL
Price: 116 USD
Availability: InStock

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Nicotinic acid, 3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B₃

Select a Size

Change View

Size/SKU	Availability	Price
1 g	Estimated to ship onJanuary 08, 2027fromMILWAUKEE	$116.00

About This Item

Linear Formula:

NC₅H₄CO₂H

CAS Number:

59-67-6

Molecular Weight:

123.11

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823272

EC Number:

200-441-0

Beilstein/REAXYS Number:

109591

MDL number:

MFCD00006391

eCl@ss:

25140904

$116.00

Estimated to ship onJanuary 08, 2027Details

Request a Custom Order

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. N0700000, traceable to USP 1461003

API family

nicotinic acid

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

236-239 °C (lit.)

application(s)

pharmaceutical
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC(=O)c1cccnc1

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Niacin (Nicotinic Acid) is commonly used as a dietary supplement, and its deficiency can cause pellagra. It is involved in the synthesis of coenzymes such as NAD and NADP, which are quite essential for enzymatic reactions.
As a lipid-lowering agent, it helps in the prevention of coronary heart disease, carotid artery disease and other atherosclerotic vascular diseases.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Niacin (Nicotinic Acid) may be used as a secondary pharma standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique and reversed-phase high-performance liquid chromatography technique.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAB7604 in the slot below. This is an example certificate only and may not be the lot that you receive.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	481918	47864	N0761
Supelco PHR1276 Niacin (Nicotinic Acid)	Millipore 481918 Nicotinic Acid	Supelco 47864 Nicotinic acid	Sigma-Aldrich N0761 Nicotinic acid
description Pharmaceutical Secondary Standard; Certified Reference Material	description A component of coenzymes NAD+ and NADP+.	description analytical standard	description BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥98%
application(s) pharmaceutical pharmaceutical (small molecule)	application(s) -	application(s) pharmaceutical (small molecule) vitamins, nutraceuticals, and natural products	application(s) agriculture
technique(s) gas chromatography (GC): suitable, HPLC: suitable	technique(s) -	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) cell culture \| insect: suitable, cell culture \| mammalian: suitable, cell culture \| plant: suitable
format neat	format -	format neat	format -
Quality Level 300	Quality Level 100	Quality Level 100	Quality Level 200
grade certified reference material, pharmaceutical secondary standard	grade -	grade analytical standard	grade -
storage temp. 2-30°C	storage temp. 10-30°C	storage temp. 2-30°C	storage temp. -

Still not finding the right product?

Explore all of our products under Niacin (Nicotinic Acid)

Pictograms

GHS07

Signal Word

Warning

Hazard Codes

H319

Precautionary Statements

P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

379.4 °F - closed cup

Flash Point (°C)

193 °C - closed cup

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

1–2 of 2 Questions

Anonymous

a year ago

How can I determine the shelf life / expiration / retest date of this product?

1 answer
1. Technical Support
  
  a year ago
  
  If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
  For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
  For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
  For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
  
  Helpful?
Anonymous

2 years ago

How is shipping temperature determined? And how is it related to the product storage temperature?

1 answer
1. Technical Support
  
  2 years ago
  
  Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
  
  Helpful?

Reviews

No rating value