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SMB00971

4-Ethylphenol sodium sulfate

Synonym(s):

4-Ethylphenyl sulfate sodium salt

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About This Item

Empirical Formula (Hill Notation):
C8H9NaO4S
Molecular Weight:
224.21
NACRES:
NA.77
UNSPSC Code:
51171629
Assay:
≥98.0% (HPLC)
Form:
solid
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assay

≥98.0% (HPLC)

Quality Segment

form

solid

storage temp.

−20°C

General description

4-Ethylphenol sodium sulfate is the sodium salt of 4-Ethylphenyl sulfate (4EPS). 4-Ethylphenyl sulfate is a gut microbial metabolite derived from tyrosine, which is converted into 4-ethylphenol and subsequently sulfated in the liver. Upregulated urine 4EPS levels are found among rats prone to insulin resistance and obesity. Increased plasma 4EPS was reported in a murine model of autism, and mice treated with 4EPS displayed anxiety-like behaviours. Higher levels of 4-ethylphenylsulfate were also found in plasma, liver, heart and kidneys in a rat model of chronic kidney disease. 4EPS is a component of the urine of male rats, and both 4-ethylphenyl sulfate and 4-ethylphenol are thought to participate in pheromonal communication. p-Cresol-sulfate and 4-ethylphenyl sulfate are thought to derive from tyrosine and have similar bioactivities, however their enzymatic production may differ.

Application

Metabolomics research
Microbiome research

Other Notes

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This Item
B13796313863138
description

-

description

sulfatase substrate

description

BioUltra, ≥99.5% (KT)

description

BioUltra, ≥99.5% (KT)

form

solid

form

powder

form

-

form

-

assay

≥98.0% (HPLC)

assay

≥98% (TLC)

assay

≥99.5% (KT)

assay

≥99.5% (KT)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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Questions

1–2 of 2 Questions  
  1. Could you please provide this chemical's solubility details? 4-ethylphenol Sulfate(4EPS)

    1 answer
    1. This product has not been tested for solubility. Unfortunately, a search of the literature revealed limited information, The related compound, 4-ethylphenyl hydrogen sulfate, is soluble in ethanol and DMSO at >20 mg/mL. As this product is the sulfate sodium salt form rather that the hydrogen sulfate form listed above, it may have somewhat different rates.

      Helpful?

  2. 4-Ethylphenol sodium sulfate and 4-Ethylphenyl sulfate are both the same compound or different compounds. Can you please clarify?

    1 answer
    1. This product is the sodium salt of 4-Ethylphenol sulfate (4EPS). The sodium ionizes in solution and is not covalently bound. The solubility and stability may be different as compared to the 4-Ethylphenol sulfate, but there is no difference in the physical properties or biological activity.

      Helpful?

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