T176
4-Hydroxytamoxifen
analytical standard, (E) and (Z) isomers (50:50)
Synonym(s):
4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol, 4-OHT, cis/trans-4-Hydroxytamoxifen
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
10 mg | Available to ship TODAYfromMILWAUKEE | $95.40 |
50 mg | Available to ship TODAYfromMILWAUKEE | $380.00 |
About This Item
$95.40
Available to ship TODAYDetails
grade
analytical standard
Quality Segment
form
powder
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
solubility
ethanol: 20 mg/mL
antibiotic activity spectrum
neoplastics
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
mode of action
enzyme | inhibits
SMILES string
CC\C(c1ccccc1)=C(/c2ccc(O)cc2)c3ccc(OCCN(C)C)cc3.CC\C(c4ccccc4)=C(\c5ccc(O)cc5)c6ccc(OCCN(C)C)cc6
InChI
1S/2C26H29NO2/c2*1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h2*5-17,28H,4,18-19H2,1-3H3/b26-25+;26-25-
InChI key
ZJLDABGSDWXVGE-BDSXMVAQSA-N
Gene Information
human ... ESR1(2099), ESR2(2100), ESRRG(2104), IL6(3569)
rat ... Ar(24208), Esr1(24890), Esr2(25149)
General description
Application
- Determination of tamoxifen and its three metabolites from dried blood spot (DBS) discs by ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS)
- Simultaneous estimation of tamoxifen, 4-hydroxytamoxifen, and endoxifen from DBS samples by UHPLC-MS/MS
- Development and validation of a non-aqueous capillary electrophoretic (NACE) method coupled with capacitively coupled contactless conductivity detection (C4D) to analyze tamoxifen and its three main metabolites after their liquid-liquid extraction (LLE) from human plasma samples obtained from breast cancer patients
- Multi-residue analysis of human plasma samples to quantify tamoxifen and its degradation products using the non-aqueous capillary electrophoretic (NACE) method combined with UV-detection
- Combined detection of tamoxifen and centchroman, along with their degradation products in human plasma samples by LC-ESI-MS/MS
Biochem/physiol Actions
Other Notes
1 of 1
This Item | |||
|---|---|---|---|
| description analytical standard, (E) and (Z) isomers (50:50) | description ≥70% Z isomer (remainder primarily E-isomer) | description 5 mg/mL in ethanol: isopropanol (95:5) | description (E) and (Z) isomers (50:50), analytical standard |
| grade analytical standard | grade - | grade - | grade analytical standard |
| format neat | format - | format - | format neat |
| technique(s) gas chromatography (GC): suitable, HPLC: suitable | technique(s) - | technique(s) - | technique(s) gas chromatography (GC): suitable, HPLC: suitable |
| mode of action enzyme | inhibits | mode of action enzyme | inhibits | mode of action - | mode of action - |
| Gene Information human ... ESR1(2099), ESR2(2100), ESRRG(2104), IL6(3569) | Gene Information human ... ESR1(2099), ESR2(2100), ESRRG(2104), IL6(3569) | Gene Information - | Gene Information - |
| antibiotic activity spectrum neoplastics | antibiotic activity spectrum neoplastics | antibiotic activity spectrum - | antibiotic activity spectrum - |
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signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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