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10791

Antipain

>50000 U/mg

Synonym(s):

[(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L-valyl-argininal

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Size/SKUAvailabilityPrice
5 mg
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40 100 HUF
25 mg
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144 000 HUF

About This Item

Empirical Formula (Hill Notation):
C27H44N10O6
CAS Number:
Molecular Weight:
604.70
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
EC Number:
253-631-0
Beilstein/REAXYS Number:
6837629
MDL number:

40 100 HUF


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Quality Segment

specific activity

>50000 U/mg

input

general use sample(s)

mode of action

enzyme | inhibits

storage temp.

−20°C

SMILES string

[H]C(=O)C(CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)N[C@@H](Cc1ccccc1)C(O)=O)C(C)C

InChI

1S/C27H44N10O6/c1-16(2)21(23(40)34-18(15-38)10-6-12-32-25(28)29)37-22(39)19(11-7-13-33-26(30)31)35-27(43)36-20(24(41)42)14-17-8-4-3-5-9-17/h3-5,8-9,15-16,18-21H,6-7,10-14H2,1-2H3,(H,34,40)(H,37,39)(H,41,42)(H4,28,29,32)(H4,30,31,33)(H2,35,36,43)/t18?,19-,20-,21-/m0/s1

InChI key

SDNYTAYICBFYFH-KTYMLHDXSA-N

General description

Chemical structure: peptide

Biochem/physiol Actions

Reversible inhibitor of serine/cysteine proteases and some trypsin-like serine proteases. Its action resembles leupeptin; however, its plasmin inhibition is less and its cathepsin A inhibition is more than that observed with leupeptin. Chronic administration can reduce the frequency of chemically induced transformation in BALB/c-/3T3 cells.
Inhibits serine/cysteine proteases and some trypsin-like proteases. Compare activity to that of leupeptin. Used to evaluate the role of proteases in cell transformations. Used to help identify new proteases.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Protease inhibitor
1 U corresponds to the amount of inhibitor which reduces the trypsin activity by 1 BAEE-U. (1 BAEE-U is the amount of enzyme which increases the absorbance at 253 nm by 0.001 per minute at pH 7.6 and 25°C; BAEE, Cat. No. 12880, as substrate)

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A6191A667111702
description

>50000 U/mg

description

protease inhibitor

description

-

description

from Bacillus licheniformis, ≥65 IU/mg

Quality Level

100

Quality Level

300

Quality Level

200

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

specific activity

>50000 U/mg

specific activity

-

specific activity

-

specific activity

≥65 IU/mg

mode of action

enzyme | inhibits

mode of action

enzyme | inhibits

mode of action

enzyme | inhibits

mode of action

cell wall synthesis | interferes


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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