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21953

5(6)-Carboxytetramethylrhodamine

BioReagent, suitable for fluorescence, ≥85% (sum of isomers, HPCE)

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Size/SKUAvailabilityPrice
100 mg

Estimated to ship onNovember 04, 2026fromMILWAUKEE

$327.00
500 mg

Available to ship TODAY

$1,090.00

About This Item

Empirical Formula (Hill Notation):
C25H22N2O5
CAS Number:
Molecular Weight:
430.45
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:

$327.00


Estimated to ship onNovember 04, 2026Details


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product line

BioReagent

Quality Segment

assay

≥85% (sum of isomers, HPCE)

form

solid

mp

≥300 °C (lit.)

solubility

DMF: soluble, DMSO: soluble

fluorescence

λex 543 nm; λem 572 nm in methanol

suitability

suitable for fluorescence

SMILES string

CN(C)c1ccc2c(Oc3cc(ccc3C24OC(=O)c5cc(ccc45)C(O)=O)N(C)C)c1.CN(C)c6ccc7c(Oc8cc(ccc8C79OC(=O)c%10ccc(cc9%10)C(O)=O)N(C)C)c6

InChI

1S/2C25H22N2O5/c1-26(2)15-6-9-19-21(12-15)31-22-13-16(27(3)4)7-10-20(22)25(19)18-8-5-14(23(28)29)11-17(18)24(30)32-25;1-26(2)15-6-9-18-21(12-15)31-22-13-16(27(3)4)7-10-19(22)25(18)20-11-14(23(28)29)5-8-17(20)24(30)32-25/h2*5-13H,1-4H3,(H,28,29)

InChI key

LBUFYZITRTUEFI-UHFFFAOYSA-N

Application

5(6)-Carboxytetramethylrhodamine (TAMRA, TMR) may be used as a fluorescence probe to study the distribution of molecules such as cell-penetrating peptides (CPPs) and as fluorescence partner in applications such as two-dimensional fluorescence intensity distribution analysis (2D-FIDA), luminescence resonance energy transfer (LRET) and fluorescence resonance energy transfer (FRET).
Reacts with primary and secondary amine groups on proteins, nucleic acids and other biomolecules.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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This Item
21955C2734
description

BioReagent, suitable for fluorescence, ≥85% (sum of isomers, HPCE)

description

BioReagent, suitable for fluorescence, ≥70% (coupling to amines)

description

-

suitability

suitable for fluorescence

suitability

suitable for fluorescence

suitability

-

fluorescence

λex 543 nm; λem 572 nm in methanol

fluorescence

λex 543 nm; λem 576 nm in methanol, λex 554 nm; λem 584 nm in 0.1 M phosphate pH 8.0

fluorescence

λex ~543 nm; λem ~570 nm in methanol

form

solid

form

powder

form

solid

solubility

DMSO: soluble, DMF: soluble

solubility

acetonitrile: soluble, methanol: soluble, DMF: soluble

solubility

water: slightly soluble

Quality Level

100

Quality Level

100

Quality Level

100

assay

≥85% (sum of isomers, HPCE)

assay

≥70% (coupling to amines)

assay

≥95% (HPLC)


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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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