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39220

Dansyl chloride

Name: Dansyl chloride
Brand: SIGMA
Price: 137 CHF

suitable for fluorescence, BioReagent, ≥99.0% (HPLC)

Synonyme(s) :

1-Dimethylaminonaphthalene-5-sulfonyl chloride, 5-(Dimethylamino) naphthalene-1-sulfonyl chloride, DNS Chloride, DNSCl, 5-(Dimethylamino)naphthalene-1-sulfonyl chloride

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À vous/Référence	Disponibilité	Prix
1 g	Vérifier la disponibilité des articles du panier	137.00 CHF
5 g	Vérifier la disponibilité des articles du panier	559.00 CHF
50 g	Vérifier la disponibilité des articles du panier	2 670.00 CHF

A propos de cet article

Formule empirique (notation de Hill) :

C₁₂H₁₂ClNO₂S

Numéro CAS:

605-65-2

Poids moléculaire :

269.75

UNSPSC Code:

12352101

NACRES:

NA.32

PubChem Substance ID:

329755828

EC Number:

210-092-6

Beilstein/REAXYS Number:

2217205

MDL number:

MFCD00003985

137.00 CHF

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Propriétés

product line

BioReagent

Quality Segment

200

assay

≥99.0% (HPLC)

form

powder

mol wt

269.75 g/mol

composition

Carbon Content, 53.57% , Hydrogen Content, 4.49% , Nitrogen Content, 5.00%

concentration

≤100% (5-dimethylaminonaphthalene-1-sulphonyl chloride)

color

orange-yellow, light yellow to dark yellow, yellow-orange, light yellow-orange to dark orange

mp

72-74 °C (lit.)

solubility

acetone: 0.2 g/10 mL

fluorescence

λ_ex 337 nm; λ_em 492 nm in chloroform (after derivatization with hexylamine)

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O

InChI

1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3

InChI key

XPDXVDYUQZHFPV-UHFFFAOYSA-N

Description

General description

Dansyl Chloride, also known as 5-dimethylamino naphthalene-1-sulfonyl chloride, is a pre-column derivatization reagent. [1] After the derivatization reaction, the fluorescent derivatives are analyzed using several analytical methods like NMR, IR, UV-vis, and fluorescence microscopy.[2] Dansyl Chloride is a typical aromatic sulphonyl chloride that reacts with various bases, resulting in derivatives with variable stability.

Application

A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.

Dansyl Chloride is used as a derivatization reagent to study extensive metabolism and low doses of ethinylestradiol administered during pre-clinical studies.[3] Studies conducted to determine bisphenols in human serum through the HPLC method used Dansyl Chloride to obtain the derivative products.[4] Dansyl Chloride derivatives are suitable for LC/MS determination and characterization of glyphosate, aminomethylphosphonic acid (AMPA), and glufosinate from food samples.[1]

Comparer avec des articles similaires

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1 of 1

Cet article	D2625	311155	03641
Sigma-Aldrich 39220 Dansyl chloride	Sigma-Aldrich D2625 Dansyl chloride	Sigma-Aldrich 311155 Dansyl Chloride	Supelco 03641 Dansyl chloride
assay ≥99.0% (HPLC)	assay ≥99% (HPLC)	assay ≥99% (LC/MS)	assay ≥99.0% (HPLC)
concentration ≤100% (5-dimethylaminonaphthalene-1-sulphonyl chloride)	concentration -	concentration -	concentration -
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 100
product line BioReagent	product line BioReagent	product line -	product line -
form powder	form powder and chunks	form solid	form powder or crystals
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C

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pictograms

GHS05

signalword

Danger

hcodes

H290,H314

pcodes

P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338 + P310

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Classe de stockage

8A - Combustible corrosive hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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