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44977

DISBAC2(3), Voltage Sensitive Probe

≥98% (HPLC)

Synonym(s):

5-[3-(1,3-Diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propen-1-ylidene]-1,3-diethyldihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione, Bis(1,3-diethylthiobarbituric acid)trimethine oxonol

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Pack SizeSKUAvailabilityPrice
1 mg
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$545.00

About This Item

Empirical Formula (Hill Notation):
C19H24N4O4S2
CAS Number:
47623-98-3
Molecular Weight:
436.55
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
329756577
EC Number:
256-325-5
Beilstein/REAXYS Number:
1232950
MDL number:
MFCD07437858

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Quality Level

100

assay

≥98% (HPLC)

fluorescence

λex 535 nm; λem 560 nm in DMSO

suitability

complies for Infrared spectrum

storage temp.

−20°C

SMILES string

CCN1C(=O)C(\C=C\C=C2\C(=O)N(CC)C(=S)N(CC)C2=O)C(=O)N(CC)C1=S

InChI

1S/C19H24N4O4S2/c1-5-20-14(24)12(15(25)21(6-2)18(20)28)10-9-11-13-16(26)22(7-3)19(29)23(8-4)17(13)27/h9-12H,5-8H2,1-4H3/b10-9+

InChI key

VJYNRXFXHKIGLT-MDZDMXLPSA-N

Application

DISBAC2(3), Voltage Sensitive Probe is used for single-cell fluorescence imaging of transmembrane conductance and potential change.

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8.02940930709SML2683
DISBAC2(3), Voltage Sensitive Probe ≥98% (HPLC)

Sigma-Aldrich

44977

DISBAC2(3), Voltage Sensitive Probe

2,3-Dichloro-5,6-dicyano-p-benzoquinone for synthesis

Sigma-Aldrich

8.02940

2,3-Dichloro-5,6-dicyano-p-benzoquinone

Pomalidomide-piperazine-propanoic acid ≥95.0%

Sigma-Aldrich

930709

Pomalidomide-piperazine-propanoic acid

dBET6 ≥98% (HPLC)

Sigma-Aldrich

SML2683

dBET6

suitability

complies for Infrared spectrum

suitability

-

suitability

-

suitability

-

fluorescence

λex 535 nm; λem 560 nm in DMSO

fluorescence

-

fluorescence

-

fluorescence

-

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

-

storage temp.

−20°C

storage temp.

2-30°C

storage temp.

2-8°C

storage temp.

−20°C

assay

≥98% (HPLC)

assay

-

assay

≥95.0%

assay

≥98% (HPLC)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH0621
BCCF8360
BCCD1917
BCBH2187V

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In situ study of the membrane potential in microvascular endothelial cells using a fluorescent probe.
K Miao et al.
Microvascular research, 48(1), 135-142 (1994-07-01)
Alexander S Tatikolov et al.
Biophysical chemistry, 107(1), 33-49 (2004-02-12)
Non-covalent interactions between polymethine dyes of various types (cationic and anionic thiacarbocyanines as well as anionic oxonols and tetracyanopolymethines) and human serum albumin (HSA) were studied by means of absorption, fluorescence and circular dichroism (CD) spectroscopies. Complexation with the protein
S Amoroso et al.
Biochimica et biophysica acta, 1239(1), 67-73 (1995-10-04)
In this study the effect of the A1 agonist 2-chloro-N6-cyclopentyladenosine (CCPA) on bis(1,3-diethylthiobarbituric acid)trimethine oxonol (bisoxonol)-monitored membrane potential in cerebrocortical nerve endings was evaluated. CCPA (30, 100 and 300 microM) caused a dose-dependent decrease of high K(+)- and veratridine-induced membrane
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Global Trade Item Number

SKUGTIN
44977-1MG04061823367226

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