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63705

Sodium 2-mercaptoethanesulfonate

Name: Sodium 2-mercaptoethanesulfonate
Brand: SIGMA

BioXtra, ≥98.0% (RT)

Sinonimo/i:

2-Mercaptoethanesulfonic acid sodium salt, Coenzyme M sodium salt, HS-CoM Na, MESNA

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Informazioni su questo articolo

Formula condensata:

HSCH₂CH₂SO₃Na

Numero CAS:

19767-45-4

Peso molecolare:

164.18

UNSPSC Code:

12161504

NACRES:

NA.25

PubChem Substance ID:

57651954

EC Number:

243-285-9

Beilstein/REAXYS Number:

3657828

MDL number:

MFCD00007535

Assay:

≥98.0% (RT)

Quality level:

200

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Proprietà

product line

BioXtra

Quality Level

200

assay

≥98.0% (RT)

loss

≤2.0% loss on drying, 20 °C (HV)

cation traces

Ca: ≤150 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤100 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

SMILES string

[Na+].[O-]S(=O)(=O)CCS

InChI

1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1

InChI key

XOGTZOOQQBDUSI-UHFFFAOYSA-M

Descrizione

Application

2-Mercaptoethanesulfonic acid sodium salt (Coenzyme M sodium salt, MESNA) is used as an antioxidant and cytoprotective agent in a wide variety of applications from protection from toxicity of therapeutic agents, such as cyclophosphamide to prevention from brain injury damage.

Other Notes

Biosynthesis of coenzyme M

Biosynthesis of coenzyme Mcitation

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Questo articolo	71916	8.10595	M1511
Sigma-Aldrich 63705 Sodium 2-mercaptoethanesulfonate	Sigma-Aldrich 71916 Sodium 2-propanethiolate	Sigma-Aldrich 8.10595 Sodium 2-mercaptoethanesulfonate	Supelco M1511 Sodium 2-mercaptoethanesulfonate
assay ≥98.0% (RT)	assay ≥90.0% (RT)	assay -	assay ≥98.0% (titration)
Quality Level 200	Quality Level 100	Quality Level 200	Quality Level 200
product line BioXtra	product line -	product line -	product line -
loss ≤2.0% loss on drying, 20 °C (HV)	loss -	loss -	loss -
cation traces Ca: ≤150 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤100 mg/kg, Mn: ≤5 mg/kg, Pb: ≤5 mg/kg	cation traces -	cation traces -	cation traces -

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Coordination of methyl coenzyme M and coenzyme M at divalent and trivalent nickel cyclams: model studies of methyl coenzyme M reductase active site.

Jun-ichi Nishigaki et al.

Inorganic chemistry, 51(6), 3690-3697 (2012-03-10)

Divalent and trivalent nickel complexes of 1,4,8,11-tetraazacyclotetradecane, denoted as cyclam hereafter, coordinated by methyl coenzyme M (MeSCoM(-)) and coenzyme M (HSCoM(-)) have been synthesized in the course our model studies of methyl coenzyme M reductase (MCR). The divalent nickel complexes

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Numero articolo commerciale globale

SKU	GTIN
63705-50G	04061832723556
63705-10G	04061832723518

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