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63705

Sodium 2-mercaptoethanesulfonate

BioXtra, ≥98.0% (RT)

Synonym(s):

2-Mercaptoethanesulfonic acid sodium salt, Coenzyme M sodium salt, HS-CoM Na, MESNA

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Pack SizeSKUAvailabilityPrice
10 g
Please contact Customer Service for Availability
$251.00
50 g
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$891.00

About This Item

Linear Formula:
HSCH2CH2SO3Na
CAS Number:
Molecular Weight:
164.18
UNSPSC Code:
12161504
NACRES:
NA.25
PubChem Substance ID:
EC Number:
243-285-9
Beilstein/REAXYS Number:
3657828
MDL number:
Assay:
≥98.0% (RT)
Quality level:

$251.00


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product line

BioXtra

Quality Level

assay

≥98.0% (RT)

loss

≤2.0% loss on drying, 20 °C (HV)

cation traces

Ca: ≤150 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤100 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

SMILES string

[Na+].[O-]S(=O)(=O)CCS

InChI

1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1

InChI key

XOGTZOOQQBDUSI-UHFFFAOYSA-M

Application

2-Mercaptoethanesulfonic acid sodium salt (Coenzyme M sodium salt, MESNA) is used as an antioxidant and cytoprotective agent in a wide variety of applications from protection from toxicity of therapeutic agents, such as cyclophosphamide to prevention from brain injury damage.

Other Notes

Biosynthesis of coenzyme M
Biosynthesis of coenzyme Mcitation

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assay

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assay

≥90.0% (RT)

assay

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assay

≥98.0% (titration)

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

product line

BioXtra

product line

-

product line

-

product line

-

cation traces

Ca: ≤150 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤100 mg/kg, Mn: ≤5 mg/kg, Pb: ≤5 mg/kg, Cr: ≤5 mg/kg, Mg: ≤5 mg/kg, Zn: ≤5 mg/kg, Cd: ≤5 mg/kg, Ni: ≤5 mg/kg

cation traces

-

cation traces

-

cation traces

-

loss

≤2.0% loss on drying, 20 °C (HV)

loss

-

loss

-

loss

-


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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R.H. White
Biochemistry, 24, 6487-6487 (1985)
Janelle B Perkins et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 17(24), 7743-7753 (2011-10-27)
To determine the maximum tolerated dose (MTD) of topotecan in combination with ifosfamide, mesna, and etoposide (TIME), followed by autologous hematopoietic cell transplant (HCT), in patients with chemotherapy-refractory malignancies. Patients were treated with (in mg/m(2)/d) ifosfamide 3,333, mesna 3,333, and
Jun-ichi Nishigaki et al.
Inorganic chemistry, 51(6), 3690-3697 (2012-03-10)
Divalent and trivalent nickel complexes of 1,4,8,11-tetraazacyclotetradecane, denoted as cyclam hereafter, coordinated by methyl coenzyme M (MeSCoM(-)) and coenzyme M (HSCoM(-)) have been synthesized in the course our model studies of methyl coenzyme M reductase (MCR). The divalent nickel complexes



Global Trade Item Number

SKUGTIN
63705-50G04061832723556
63705-10G04061832723518

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