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76548

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

≥97.0% (TLC)

Synonym(s):

(9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, 1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine, 1,2-dideoyl, L-β,γ-Dioleoyl-α-cephalin, DOPE, Dioleoyl phosphatidylethanolamine, PE(18:1(9Z)/18:1(9Z))

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Size/SKUAvailabilityPrice
100 mg

Available to ship TODAYfromMILWAUKEE

$260.00
1 g

Estimated to ship TODAYfromSAINT LOUIS

$1,040.00

About This Item

Empirical Formula (Hill Notation):
C41H78NO8P
CAS Number:
Molecular Weight:
744.03
UNSPSC Code:
51191904
NACRES:
NA.85
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1718431

$260.00


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biological source

synthetic

Quality Segment

assay

≥97.0% (TLC)

form

solid

functional group

amine

lipid type

phosphoglycerides

storage temp.

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)OCC(COP(O)(=O)OCCN)OC(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-

InChI key

MWRBNPKJOOWZPW-CLFAGFIQSA-N

Application

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) forms heterogenous liposomes with N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methylsulfate (DOTAP), which are used as delivery vehicles for therapeutic agents .

Biochem/physiol Actions

DOPE in mixed membranes have been found to decrease fluorescence lifetime and increase acyl-chain order. DOPE is an essential component of cationic liposomes designed to deliver DNA into gliosarcoma and kidney cell lines (gene therapy).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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This Item
42490P1223D0138
description

≥97.0% (TLC)

description

≥99.0% (10 mg phospholipid per ml CHCl3, TLC)

description

≥99% (GC), ≥98% (TLC), lyophilized powder

description

≥97%

assay

≥97.0% (TLC)

assay

≥99.0% (10 mg phospholipid per ml CHCl3, TLC)

assay

≥99% (GC), ≥98% (TLC)

assay

≥97%

biological source

synthetic

biological source

-

biological source

synthetic

biological source

semisynthetic

functional group

amine

functional group

phospholipid

functional group

phospholipid

functional group

ether

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

form

solid

form

liquid

form

lyophilized powder

form

liquid

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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