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76904

Vecuronium bromide

Synonym(s):

1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-piperidinium bromide

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Pack SizeSKUAvailabilityPrice
10 mg
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$203.00

About This Item

Empirical Formula (Hill Notation):
C34H57BrN2O4
CAS Number:
50700-72-6
Molecular Weight:
637.73
UNSPSC Code:
51152000
NACRES:
NA.77
PubChem Substance ID:
329767429
EC Number:
256-723-9
Beilstein/REAXYS Number:
4837308
MDL number:
MFCD00867762

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biological source

synthetic

Quality Level

100

assay

≥97.0% (TLC)

form

powder or crystals

functional group

carboxylic acid

SMILES string

[Br-].CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@H](CC[C@@]4(C)[C@H]3C[C@@H]([C@@H]4OC(C)=O)[N+]5(C)CCCCC5)[C@@]2(C)C[C@@H]1N6CCCCC6

InChI

1S/C34H57N2O4.BrH/c1-23(37)39-31-20-25-12-13-26-27(34(25,4)22-29(31)35-16-8-6-9-17-35)14-15-33(3)28(26)21-30(32(33)40-24(2)38)36(5)18-10-7-11-19-36;/h25-32H,6-22H2,1-5H3;1H/q+1;/p-1/t25-,26+,27-,28-,29-,30-,31-,32-,33-,34-;/m0./s1

InChI key

VEPSYABRBFXYIB-PWXDFCLTSA-M

Gene Information

human ... CHRNA1(1134), CHRNB1(1140), CHRND(1144), CHRNE(1145), CHRNG(1146)

Biochem/physiol Actions

Vecuronium Bromide is an aminosteroidal neuromuscular blocking agent. It relaxes the skeletal muscle and decreases oxygen consumption during surgery. It competes with acetylcholine and bind to cholinergic receptors at neuromuscular junctions.[1][2]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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This Item
1711155BP1167Y0000561
Vecuronium bromide

Sigma-Aldrich

76904

Vecuronium bromide

Vecuronium bromide United States Pharmacopeia (USP) Reference Standard

USP

1711155

Vecuronium bromide

Vecuronium bromide British Pharmacopoeia (BP) Reference Standard

BP1167

Vecuronium bromide

Vecuronium bromide European Pharmacopoeia (EP) Reference Standard

Y0000561

Vecuronium bromide

functional group

carboxylic acid

functional group

-

functional group

-

functional group

-

biological source

synthetic

biological source

-

biological source

-

biological source

-

assay

≥97.0% (TLC)

assay

-

assay

-

assay

-

form

powder or crystals

form

-

form

solid

form

-

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

-

Gene Information

human ... CHRNA1(1134), CHRNB1(1140), CHRND(1144), CHRNE(1145), CHRNG(1146)

Gene Information

human ... CHRNA1(1134), CHRNB1(1140), CHRND(1144), CHRNE(1145), CHRNG(1146)

Gene Information

human ... CHRNA1(1134), CHRNB1(1140), CHRND(1144), CHRNE(1145), CHRNG(1146)

Gene Information

human ... CHRNA1(1134), CHRNB1(1140), CHRND(1144), CHRNE(1145), CHRNG(1146)

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN5990
BCCK9926
BCCJ5183
BCCF6335
BCCB3328

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Hong Wang et al.
Acta pharmacologica Sinica, 32(12), 1454-1459 (2011-10-12)
To investigate the effect of magnesium sulfate and its interaction with the non-depolarizing muscle relaxant vecuronium at adult muscle-type acetylcholine receptors in vitro. Adult muscle-type acetylcholine receptors were expressed in HEK293 cells. Drug-containing solution was applied via a gravity-driven perfusion
Shawn P Vorce et al.
Journal of analytical toxicology, 32(6), 422-427 (2008-07-26)
The apparent recreational use of an aminosteroidal non-depolarizing neuromuscular blocking agent, vecuronium, is reported in this postmortem investigation. A quantitative method for the analysis of vecuronium and its active metabolite, 3-desacetylvecuronium, in blood and tissue samples was developed using liquid
Hong WANG et al.
Acta pharmacologica Sinica, 31(12), 1541-1546 (2010-11-26)
to investigate the changing resistance to nondepolarizing muscle relaxants (NDMRs) during the first month after denervation. the denervated and innervated skeletal muscle cells were examined on days 1, 4, 7, 14, 21, and 28 after denervation. Individual denervated and innervated
View All Related Papers

Global Trade Item Number

SKUGTIN
15469-1G04061826100967
76904-10MG04061832924878

Questions

  1. Please let us know the next retest/Expiry date if it is not mentioned in the COA or bottle given for Vecuronium Bromide, Product Number 76904, Batch Number BCCJ5183, thanks. Or please guide, how to check the same

    1 answer

    1. This product is not assigned an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one-year warranty from the date of shipment.

      For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.

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