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95220

Ergocalciferol

≥98.0% (sum of enantiomers, HPLC)

Synonym(s):

Calciferol, Ercalciol, Ergosterol irradiated, Irradiated ergosterol, Vitamin D2

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Pack SizeSKUAvailabilityPrice
1 g

Estimated to ship TODAYfromSAINT LOUIS

$113.00
5 g

Estimated to ship TODAYfromSAINT LOUIS

$347.00

About This Item

Empirical Formula (Hill Notation):
C28H44O
CAS Number:
50-14-6
Molecular Weight:
396.65
NACRES:
NA.79
PubChem Substance ID:
57653661
eCl@ss:
34058017
UNSPSC Code:
12352205
EC Number:
200-014-9
MDL number:
MFCD00166988
Beilstein/REAXYS Number:
1916682

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biological source

synthetic

Quality Segment

100

assay

≥98.0% (sum of enantiomers, HPLC)

form

powder

optical activity

[α]20/D +105±2°, c = 4% in ethanol

color

colorless to white

mp

114-118 °C

storage temp.

2-8°C

SMILES string

CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C

InChI

1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1

InChI key

MECHNRXZTMCUDQ-RKHKHRCZSA-N

Gene Information

human ... VDR(7421)

General description

Ergocalciferol or viosterol is obtained from irradiated ergosterol. It represents plant source of vitamin D.
Ergocalciferol is one of the two forms of supplemental vitamin D available. It is a fat-soluble vitamin.[1][2]

Application

Ergocalciferol has been used as a standard to measure vitamin D3 levels in food samples.

Biochem/physiol Actions

Ergocalciferol (vitamin D2) and 25-Hydroxycholecalciferol (vitamin D3) are the two form of vitamin D which are activated in vivo by hydroxylation. Vitamin D2 and D3 may be used in a wide range of studies to assess their effects on function such as immune function and calcium homeostasis.
Ergocalciferol (vitamin D2) has less potential than cholecalciferol (vitamin D3) in treating vitamin deficiency related disorders in humans. Supplementation of adequate dose of vitamin D2 prevents infantile rickets and is capable of curing adult osteomalacia.[1]

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This Item
E0900000E5750Y0001375
Ergocalciferol ≥98.0% (sum of enantiomers, HPLC)

Sigma-Aldrich

95220

Ergocalciferol

Ergocalciferol European Pharmacopoeia (EP) Reference Standard

E0900000

Ergocalciferol

Ergocalciferol 40,000,000 USP units/g

Sigma-Aldrich

E5750

Ergocalciferol

Ergocalciferol for system suitability European Pharmacopoeia (EP) Reference Standard

Y0001375

Ergocalciferol for system suitability

assay

≥98.0% (sum of enantiomers, HPLC)

assay

-

assay

≥97%

assay

-

biological source

synthetic

biological source

synthetic

biological source

synthetic (organic)

biological source

-

form

powder

form

solid

form

powder

form

-

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

−20°C

color

colorless to white

color

-

color

white to off-white

color

white

mp

114-118 °C

mp

114-118 °C (lit.)

mp

114-118 °C (lit.)

mp

114-118 °C (lit.)

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL6651
BCCP3249
BCCH2252
BCCK4838
BCCG2932

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Global Trade Item Number

SKUGTIN
95220-5G04061835515691
95220-1G04061833315750

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What is the recommended method for storing stock solutions of item 95220, Ergocalciferol dissolved in ethanol?

    1 answer

    1. For short-term storage (days to weeks), it is recommended to store the stock solution of item 95220, Ergocalciferol dissolved in ethanol, at 0 - 4°C. For long-term storage, the stock solution should be sealed and stored below -20°C. Typically, the stock solution can be kept for several months. Before use, it is advisable to allow the vial to reach room temperature for at least an hour.

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