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AMAB90664

Monoclonal Anti-CTCF antibody produced in mouse

Name: Monoclonal Anti-CTCF antibody produced in mouse
Brand: SIGMA
Price: 3468 BRL

Prestige Antibodies^® Powered by Atlas Antibodies, clone CL0305, purified immunoglobulin, buffered aqueous glycerol solution

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Para você/SKU	Disponibilidade	Preço
100 μL	Verificar disponibilidade no carrinho	R$ 3.468,00

Sobre este item

NACRES:

NA.43

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

CL0305, monoclonal

Application:

IF, IHC

Citations:

R$ 3.468,00

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Propriedades

biological source

mouse

Quality Segment

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

CL0305, monoclonal

product line

Prestige Antibodies^® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

human

concentration

1 mg/mL

technique(s)

immunoblotting: 1 μg/mL, immunofluorescence: 2-10 μg/test (Fixation/Permeabilization: PFA/Triton X-100), immunohistochemistry: 1:500- 1:1000

pH range

7.2-7.4

isotype

IgG1

Ensembl | human accession no.

ENSG00000102974

UniProt accession no.

P49711

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CTCF(10664)

Descrição

General description

The CCCTC-binding factor (CTCF) gene is mapped to human chromosome 16q22.1. CTCF is a transcription factor and has 11 zinc finger motifs critical for binding to genomes.

Immunogen

Recombinant protein corresponding to CCCTC-binding factor (zinc finger protein)

Application

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies^® protocols and other useful information.

Biochem/physiol Actions

CCCTC-binding factor (CTCF) protein controls organization of chromatin architecture and gene expression. It regulates gene replication, recombination and splicing. CTCF regulates the gene rearrangement events during immunoglobulin synthesis. CTCF helps in the binding of cohesion protein to chromatin during cell division. Mutations in CTCF gene impacts gene regulation leading to growth retardation and developmental disorder. Mutations in the zinc finger motifs of CTCF are implicated in tumor progression.(10)

Features and Benefits

Prestige Antibodies^® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies^® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
Protein array of 364 human recombinant protein fragments.

Physical form

100UL pack size is provided in a solution, in PBS(phosphate-buffered saline), pH 7.2, containing 40% glycerol and 0.02% sodium azide.

Large pack size of 1ml (at 1mg/ml) is available in PBS only, purified, biocide free, carrier free and glycerol free. Order here

Preparation Note

Upon arrival, mix gently and aliquot to avoid repeated freeze-thaw cycles

Legal Information

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Este Item	AMAB90666	AMAB90663	SAB1402162
Sigma-Aldrich AMAB90664 Monoclonal Anti-CTCF antibody produced in mouse	Sigma-Aldrich AMAB90666 Monoclonal Anti-CTCF antibody produced in mouse	Sigma-Aldrich AMAB90663 Monoclonal Anti-CTCF antibody produced in mouse	Sigma-Aldrich SAB1402162 Monoclonal Anti-CTGF antibody produced in mouse
description Prestige Antibodies^® Powered by Atlas Antibodies, clone CL0305, purified immunoglobulin, buffered aqueous glycerol solution	description Prestige Antibodies^® Powered by Atlas Antibodies, clone CL0307, purified immunoglobulin, buffered aqueous glycerol solution	description Prestige Antibodies^® Powered by Atlas Antibodies, clone CL0304, purified immunoglobulin, buffered aqueous glycerol solution	description clone 2C11, purified immunoglobulin, buffered aqueous solution
species reactivity human	species reactivity human	species reactivity human	species reactivity human
Gene Information human ... CTCF(10664)	Gene Information human ... CTCF(10664)	Gene Information human ... CTCF(10664)	Gene Information human ... CTGF(1490)
antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified immunoglobulin
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source mouse	biological source mouse	biological source mouse	biological source mouse
clone CL0305, monoclonal	clone CL0307, monoclonal	clone CL0304, monoclonal	clone 2C11, monoclonal

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Classe de armazenamento

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c