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HPA017286

Anti-STRN antibody produced in rabbit

Name: Anti-STRN antibody produced in rabbit
Brand: SIGMA
Price: 564 EUR

Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Synonyme(s) :

Anti-Striatin

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À vous/Référence	Disponibilité	Prix
100 μL	Vérifier la disponibilité des articles du panier	564,00 €

A propos de cet article

UNSPSC Code:

12352203

NACRES:

NA.41

Human Protein Atlas Number:

HPA017286

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IF, IHC

Citations:

564,00 €

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Propriétés

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

product line

Prestige Antibodies^® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

human

technique(s)

immunoblotting: 0.04-0.4 μg/mL, immunofluorescence: 0.25-2 μg/mL, immunohistochemistry: 1:200-1:500

immunogen sequence

RALLGFSSDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTKEALKEFDFLVTSEEGDNESRSAGDGTDWEKEDQC

UniProt accession no.

O43815

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... STRN(6801)

Description

General description

STRN (striatin, calmodulin binding protein) encodes the striatin protein belonging to the calmodulin-binding WD repeat protein family. It is composed of four putative protein-protein interaction domains, a caveolin-binding domain, a coiled-coil domain, a calcium-dependent calmodulin-binding domain, and the WD-repeat region.

Immunogen

Striatin recombinant protein epitope signature tag (PrEST)

Application

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies^® protocols and other useful information.

Biochem/physiol Actions

STRN (striatin, calmodulin binding protein) acts as a Ca²⁺-dependent scaffold protein. It conjugates with the anaplastic lymphoma kinase (ALK) gene to produce STRN-ALK fusion protein. The fusion protein retains the N-terminal caveolin-binding and coiled-coil domains of STRN fused to the intracellular juxtamembrane region of ALK. Its coiled-coil domain exerts tyrosine kinase activity and signaling of STRN-ALK.

Features and Benefits

Prestige Antibodies^® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies^® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
Protein array of 364 human recombinant protein fragments.

Physical form

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

Other Notes

Corresponding Antigen APREST72509

Legal Information

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

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Cet article	HPA003392	HPA018894	HPA012892
Sigma-Aldrich HPA017286 Anti-STRN antibody produced in rabbit	Sigma-Aldrich HPA003392 Anti-STRN3 antibody produced in rabbit	Sigma-Aldrich HPA018894 Anti-UTRN antibody produced in rabbit	Sigma-Aldrich HPA012892 Anti-STOML3 antibody produced in rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level -
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
product line Prestige Antibodies^® Powered by Atlas Antibodies	product line Prestige Antibodies^® Powered by Atlas Antibodies	product line Prestige Antibodies^® Powered by Atlas Antibodies	product line Prestige Antibodies^® Powered by Atlas Antibodies
Gene Information human ... STRN(6801)	Gene Information human ... STRN3(29966)	Gene Information human ... UTRN(7402)	Gene Information human ... STOML3(161003)

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Classe de stockage

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c