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I2018

Monoclonal Anti-Insulin antibody produced in mouse

clone K36AC10, ascites fluid

Sinônimo(s):

Insulin Antibody, Insulin Antibody - Monoclonal Anti-Insulin antibody produced in mouse

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Sobre este item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00164675
Conjugate:
unconjugated
Clone:
K36AC10, monoclonal
Application:
DB, IHC (p), RIA
Citations:
174
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biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

K36AC10, monoclonal

contains

15 mM sodium azide

species reactivity

feline, human, rat, horse, rabbit, guinea pig, bovine, monkey, sheep, canine, pig

technique(s)

dot blot: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1,000 using human or animal pancreas, radioimmunoassay: suitable

isotype

IgG1

UniProt accession no.

P01308

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... INS(3630)

General description

The antibody reacts specifically against insulin by RIA and immunocytochemistry. It exhibits cross-reactivity with human proinsulin. The antibody binds to insulin with an affinity constant of 8.8 × 109 M-1 in RIA.
The insulin gene is mapped to human chromosome 11p15.5.

Application

Monoclonal Anti-Insulin antibody produced in mouse has been used in immunoblotting assay and ELISA.
Monoclonal Anti-Insulin antibody produced in mouse was used in ELISA-based protein pin array assay to study the interactions between human αB crystalline and insulin. It was used for flow cytometric analysis of rat white blood cells and mast cells.

Biochem/physiol Actions

Insulin is a major regulatory hormone important in the metabolic processes, transport of glucose, amino acids and certain ions. It is also involved in the synthesis of nucleic acids and proteins. The biological effects of insulin are mediated by insulin receptor and it integrates multiple major signaling pathways.
Insulin is a major regulatory hormone important in the metabolic processes, transport of glucose, amino acids and certain ions. It is also involved in the synthesis of nucleic acids and proteins. The biological effects of insulin are mediated by insulin receptor and it integrates multiple major signaling pathways. Abnormal insulin secretion or function leads to diabetes mellitus, obesity and other carbohydrate metabolism disorders. Insulin is known to stimulate cell division.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Este Item
SAB4200691G2654A5316
Monoclonal Anti-Insulin antibody produced in mouse clone K36AC10, ascites fluid

Sigma-Aldrich

I2018

Monoclonal Anti-Insulin antibody produced in mouse

Anti-Insulin antibody, Mouse monoclonal clone K36AC10, purified from hybridoma cell culture

Sigma-Aldrich

SAB4200691

Anti-Insulin antibody, Mouse monoclonal

Monoclonal Anti-Glucagon antibody produced in mouse clone K79bB10, ascites fluid

Sigma-Aldrich

G2654

Monoclonal Anti-Glucagon antibody produced in mouse

Antiβ-actina monoclonal clone AC-74, ascites fluid

Sigma-Aldrich

A5316

Antiβ-actina monoclonal

clone

K36AC10, monoclonal

clone

K36AC10, monoclonal

clone

K79bB10, monoclonal

clone

AC-74, monoclonal

antibody form

ascites fluid

antibody form

purified immunoglobulin

antibody form

ascites fluid

antibody form

ascites fluid

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

conjugate

unconjugated

Gene Information

human ... INS(3630)

Gene Information

bovine ... Ins(280829)
dog ... Ins(483665)
guinea pig ... Ins(100379579)
horse ... Ins(111776000)
human ... INS(3630)
pig ... Ins(397415)
rabbit ... Ins(100009181)
rhesus monkey ... Ins(704534)

Gene Information

human ... GCG(2641)
mouse ... Gcg(14526)
rat ... Gcg(24952)

Gene Information

human ... ACTB(60)
mouse ... Actb(11461)
rat ... Actb(81822)

species reactivity

feline, human, rat, horse, rabbit, guinea pig, bovine, monkey, sheep, canine, pig

species reactivity

guinea pig, porcine, bovine (proinsulin), rat, monkey, sheep, dog, horse, human (insulin ), rabbit

species reactivity

feline, canine, mouse, guinea pig, rat, rabbit, human, pig

species reactivity

rabbit, sheep, cat, guinea pig, bovine, mouse, chicken, wide range, Hirudo medicinalis, canine, Drosophila, carp, pig, rat, human

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

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