L6545
Letrozole
≥98% (HPLC), powder, non-steroidal aromatase inhibitor
Synonym(s):
4,4′-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
10 mg | Available to ship TODAYfromMILWAUKEE | $108.00 |
50 mg | Available to ship TODAYfromMILWAUKEE | $421.00 |
About This Item
Product Name
Letrozole, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: >50 mg/mL
originator
Novartis
storage temp.
2-8°C
SMILES string
N#CC(C=C1)=CC=C1C(N2C=NC=N2)C3=CC=C(C#N)C=C3
InChI
1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
InChI key
HPJKCIUCZWXJDR-UHFFFAOYSA-N
Gene Information
human ... CYP19A1(1588)
Application
- in organoid growth assay to determine its inhibitory capacity(48)
- to investigate steroid receptor coactivator-1 (SRC-1) mediated endogenous estrogen regulation of hippocampal PSD-95(49)
- to determine its effects on tumor-induced hyperalgesia(50)
- for hormonal manipulation in rats(51)
- to study its effects on lipocalin-2 (Lcn2)(52)
- to determine its effects on mechanical hyperalgesia and aromatase expression(53)
Biochem/physiol Actions
Features and Benefits
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description European Pharmacopoeia (EP) Reference Standard | description Pharmaceutical Secondary Standard; Certified Reference Material | description British Pharmacopoeia (BP) Reference Standard |
| assay ≥98% (HPLC) | assay - | assay - | assay - |
| form powder | form - | form - | form powder |
| Quality Level 100 | Quality Level - | Quality Level 300 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-30°C | storage temp. 2-8°C |
| solubility DMSO: >50 mg/mL | solubility - | solubility - | solubility - |
| color white to off-white | color - | color - | color - |
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signalword
Warning
hcodes
Hazard Classifications
Repr. 2 - STOT RE 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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