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Anti-Osteopontin antibody produced in goat

Name: Anti-Osteopontin antibody produced in goat
Brand: SIGMA
Price: 681 USD

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-OPN

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Pack Size	SKU	Availability	Price
0.1 mg		Check Cart for Availability	$681.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD02263865

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (c), IHC, Neutral, WB

Citations:

$681.00

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Properties

biological source

goat

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse

technique(s)

capture ELISA: 0.2-0.8 μg/mL, immunohistochemistry: 5-15 μg/mL using mouse thymus tissue sections, neutralization: 1-3 μg/mL, western blot: 0.1-0.2 μg/mL

UniProt accession no.

P10923

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

mouse ... Spp1(20750)

Description

General description

The OPN (osteopontin) gene is mapped to mouse chromosome 5 E5 and codes for secreted phosphoprotein 1 and is mostly expressed in bone tissue.

Immunogen

purified recombinant mouse osteopontin expressed in NSO cells.

Biochem/physiol Actions

Osteopontin (OPN) serves as a ligand to a number of integrin receptors which are associated with cell motility, chemotaxis, invasion and cell survival. Upregulation of OPN gene is observed in tumors such as colorectal carcinomas, breast cancer and contributes to its pathogenesis. OPN is associated with obesity by mediating adipocyte inflammation and insulin resistance upon macrophage activation. OPN functions as an effector molecule in extracellular signalling and promotes fibrosis and myocyte growth.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Analysis Note

Neutralizes the biological activity of recombinant mouse osteopontin using 293 cells.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	O3389	O1139	O7264
Sigma-Aldrich O7635 Anti-Osteopontin antibody produced in goat	Sigma-Aldrich O3389 Anti-Osteopontin antibody produced in goat	Sigma-Aldrich O1139 Anti-Osteoprotegerin antibody produced in goat	Sigma-Aldrich O7264 Anti-Osteopontin antibody produced in rabbit
biological source goat	biological source goat	biological source goat	biological source rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form lyophilized powder	form lyophilized powder	form lyophilized powder	form buffered aqueous solution
species reactivity mouse	species reactivity human	species reactivity mouse	species reactivity human

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

0000500739

0000433109

0000376492

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Global Trade Item Number

SKU	GTIN
O7635-.1MG	04061833235119

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