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P4743

Anti-PUMA/bbc3, N-Terminal antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-Bcl-2 Binding Component 3, Anti-p53 Upregulated Modulator of Apoptosis

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Pack SizeSKUAvailabilityPrice
100 μg
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$557.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD04040565
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ARR, WB
Citations:
13

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biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~23 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

microarray: suitable, western blot: 2-4 μg/mL

UniProt accession no.

Q96PG8

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BBC3(27113)

General description

p53 upregulated modulator of apoptosis (PUMA) protein is a member of the B-cell lymphoma 2 (BCL2) family. It is a pro-apoptotic BCL-2 homology 3 (BH3)-only protein and has a small BH3 domain. The PUMA gene is mapped on the human chromosome at 19q13.32.

Immunogen

synthetic peptide corresponding to amino acids 2 to 16 of human PUMA-α.

Application

Anti-PUMA/bbc3, N-Terminal antibody produced in rabbit has been used in western blotting[1] and immunoprecipitation.

Biochem/physiol Actions

p53 upregulated modulator of apoptosis (PUMA) acts as a determinant of the levels of germ cells during ovarian development. It promotes apoptosis in various cellular stress insults. Deletion of the PUMA gene is observed in several kinds of human cancers.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-PUMA/bbc3, N-Terminal antibody produced in rabbit ~1 mg/mL, affinity isolated antibody, buffered aqueous solution

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Sigma-Aldrich

SAB4300342

Anti-BAD (Ab-136) antibody produced in rabbit

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Quality Level

200

Quality Level

-

Quality Level

200

Quality Level

-

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SLCN9148
SLBX7353
SLBV6705
SLBG9018V
SLBG9018

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Related Content

Min Li et al.
Pharmaceuticals (Basel, Switzerland), 16(1) (2023-01-22)
Colorectal cancer is one of the most common malignancies, and the topoisomerase inhibitor irinotecan (CPT-11)-based chemotherapeutic regimen is currently the first-line treatment with impressive therapeutic efficacy. However, irinotecan has several clinically significant side effects, including diarrhea, which limit its clinical
C Li et al.
Cancer gene therapy, 23(9), 295-302 (2016-08-06)
Oral squamous cell carcinoma (OSCC) is the most common cancer of the head and neck and is associated with a high rate of lymph node metastasis. The initial step in the metastasis and transition of tumors is epithelial-mesenchymal transition (EMT)-induced
Michelle Myers et al.
Reproduction (Cambridge, England), 148(2), 211-219 (2014-05-27)
The number of primordial follicles initially established within the ovary is influenced by the extent of germ cell death during foetal ovarian development, but the mechanisms that mediate this death have not been fully uncovered. In this study, we identified
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Global Trade Item Number

SKUGTIN
P4743-100UG04061837868351

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