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R5653

Monoclonal Anti-hnRNP-Q antibody produced in mouse

clone 18E4, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-Heterogeneous Nuclear Ribonucleoprotein-Q

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Size/SKUAvailabilityPrice
200 μL
Please contact Customer Service for Availability
€568.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD03845440
Conjugate:
unconjugated
Clone:
18E4, monoclonal
Application:
ARR, ELISA (i), IHC, IP, WB
Citations:
9

€568.00

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biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

18E4, monoclonal

form

buffered aqueous solution

mol wt

antigen 55-70 kDa

species reactivity

mouse, bovine, human, rat, canine, Xenopus, chicken

technique(s)

immunohistochemistry: suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, microarray: suitable, western blot: 1-2 μg/mL using HeLa total cell extract

isotype

IgG1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SYNCRIP(10492)

General description

Monoclonal Anti-hnRNP-Q (mouse IgG1) is derived from the 18E4 hybridoma produced by the fusion of murine myeloma cells (SP2/0 cells) and splenocytes from BALB/c mice immunized with recombinant human hnRNP-Q. Heterogeneous nuclear ribonucleoproteins-Q (hnRNP-Q) family of proteins consist of three proteins (Q1, 2, and 3) that are derived by alternative splicing from the same gene.

Immunogen

recombinant human hnRNP-Q.

Application

Monoclonal Anti-hnRNP-Q antibody produced in mouse has been used in immunoblotting and immunofluorescence. It may be used in enzyme linked immunosorbent assay (ELISA), immunoprecipitation and immunohistochemistry.

Biochem/physiol Actions

Heterogeneous nuclear ribonucleoproteins (hnRNPs) act in several biological activities such as transcription, pre- mRNA processing, cytoplasmic mRNA translation and turnover. These proteins interact with the survival of motor neurons protein (SMN) that is mutated in patients with spinal muscular atrophy (SMA). Immunodepletion of hnRNP-Q proteins and their localization in spliceosomes, indicate their important role in splicing.
The hnRNP-Q and hnRNP-R antibodies share 83% homology.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Monoclonal Anti-hnRNP-Q antibody produced in mouse clone 18E4, purified immunoglobulin, buffered aqueous solution

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Anti-hnRNP-A2/B1 antibody, Mouse monoclonal clone DP3B3, purified from hybridoma cell culture

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R4653

Anti-hnRNP-A2/B1 antibody, Mouse monoclonal

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified from hybridoma cell culture

antibody form

purified immunoglobulin

Gene Information

human ... SYNCRIP(10492)

Gene Information

human ... HNRNPC(3183)

Gene Information

human ... HNRNPU(3192)

Gene Information

human ... HNRNPA2B1(3181)
mouse ... Hnrnpa2b1(53379)
rat ... Hnrnpa2b1(362361)

species reactivity

mouse, bovine, human, rat, canine, Xenopus, chicken

species reactivity

monkey, human, chicken, hamster

species reactivity

human, monkey

species reactivity

rat, human, bovine, hamster, monkey, chicken, mouse, canine

clone

18E4, monoclonal

clone

4F4, monoclonal

clone

3G6, monoclonal

clone

DP3B3, monoclonal

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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