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Monoclonal Anti-hnRNP-Q antibody produced in mouse

Name: Monoclonal Anti-hnRNP-Q antibody produced in mouse
Brand: SIGMA
Price: 650 USD
Availability: InStock

clone 18E4, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-Heterogeneous Nuclear Ribonucleoprotein-Q

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Size/SKU	Availability	Price
200 μL	Check Cart for Availability	$650.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD03845440

Conjugate:

unconjugated

Clone:

18E4, monoclonal

Application:

ARR, ELISA (i), IHC, IP, WB

Citations:

$650.00

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Properties

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

18E4, monoclonal

form

buffered aqueous solution

mol wt

antigen 55-70 kDa

species reactivity

mouse, bovine, human, rat, canine, Xenopus, chicken

technique(s)

immunohistochemistry: suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, microarray: suitable, western blot: 1-2 μg/mL using HeLa total cell extract

isotype

IgG1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SYNCRIP(10492)

Description

General description

Monoclonal Anti-hnRNP-Q (mouse IgG1) is derived from the 18E4 hybridoma produced by the fusion of murine myeloma cells (SP2/0 cells) and splenocytes from BALB/c mice immunized with recombinant human hnRNP-Q. Heterogeneous nuclear ribonucleoproteins-Q (hnRNP-Q) family of proteins consist of three proteins (Q1, 2, and 3) that are derived by alternative splicing from the same gene.

Immunogen

recombinant human hnRNP-Q.

Application

Monoclonal Anti-hnRNP-Q antibody produced in mouse has been used in immunoblotting and immunofluorescence. It may be used in enzyme linked immunosorbent assay (ELISA), immunoprecipitation and immunohistochemistry.

Biochem/physiol Actions

Heterogeneous nuclear ribonucleoproteins (hnRNPs) act in several biological activities such as transcription, pre- mRNA processing, cytoplasmic mRNA translation and turnover. These proteins interact with the survival of motor neurons protein (SMN) that is mutated in patients with spinal muscular atrophy (SMA). Immunodepletion of hnRNP-Q proteins and their localization in spliceosomes, indicate their important role in splicing.

The hnRNP-Q and hnRNP-R antibodies share 83% homology.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	R4528	R5028	R6278
Sigma-Aldrich R5653 Monoclonal Anti-hnRNP-Q antibody produced in mouse	Sigma-Aldrich R4528 Anti-hnRNP-A1 antibody, Mouse monoclonal	Sigma-Aldrich R5028 Monoclonal Anti-hnRNP-C1/C2 antibody produced in mouse	Sigma-Aldrich R6278 Anti-hnRNP-U antibody, Mouse monoclonal
description clone 18E4, purified immunoglobulin, buffered aqueous solution	description clone 9H10, purified from hybridoma cell culture	description clone 4F4, purified immunoglobulin, buffered aqueous solution	description clone 3G6, purified from hybridoma cell culture
species reactivity mouse, bovine, human, rat, canine, Xenopus, chicken	species reactivity human, hamster, monkey, rat, bovine, mouse, canine	species reactivity monkey, human, chicken, hamster	species reactivity human, monkey
Gene Information human ... SYNCRIP(10492)	Gene Information human ... HNRNPA1(3178) mouse ... Hnrnpa1(15382) rat ... Hnrnpa1(29578)	Gene Information human ... HNRNPC(3183)	Gene Information human ... HNRNPU(3192)
antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified from hybridoma cell culture
clone 18E4, monoclonal	clone 9H10, monoclonal	clone 4F4, monoclonal	clone 3G6, monoclonal
biological source mouse	biological source mouse	biological source mouse	biological source mouse
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c