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Anti-Spectrin antibody produced in rabbit

Name: Anti-Spectrin antibody produced in rabbit
Brand: SIGMA
Price: 443 USD
Availability: InStock

whole antiserum

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0.2 mL	Check Cart for Availability	$443.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00164739

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

$443.00

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

human

technique(s)

western blot: 1:400

UniProt accession no.

P02549

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SPTA1(6708), SPTB(6710), SPTBN1(6711), SPTBN2(6712), SPTBN4(57731), SPTBN5(51332)

Description

General description

Spectrin is a multifunctional protein that has lipid-binding sites within CH (calponin-homology) tandem domains, a PH (pleckstrin homology) domain and triple helical segments. It is located on chromosome 1q23.1.

Spectrin is the major cytoskeletal component in erythrocytes. It is composed of two types of polypeptides known as α and β with molecular weights of 240 and 220 kDa, respectively. The α- and β-chains form heterotetramers which are linked end-to-end via oligomeric actin and band 4.1 protein.

Immunogen

spectrin from freshly prepared human erythrocyte ghosts.

Application

Anti-Spectrin antibody has been used in western blotting immunofluorescence and immunostaining.

Biochem/physiol Actions

Spectrins modulates the cell morphology and mechanical properties. Spectrins also participates in the cell cycle by controlling the upregulation of membrane receptors. α- and β spectrins are essential for the development of nervous system.

The antibody reacts specifically with the α and β chains of human erythrocyte spectrin.

The spectrin-based membrane skeleton is essential to provide mechanical stability and membrane integrity. It is also responsible for protein organization, trafficking and resilience of erythrocytes.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB2102292	HPA007927	MABN1727
Sigma-Aldrich S1515 Anti-Spectrin antibody produced in rabbit	Sigma-Aldrich SAB2102292 Anti-SPTAN1 antibody produced in rabbit	Sigma-Aldrich HPA007927 Anti-SPTAN1 antibody produced in rabbit	Sigma-Aldrich MABN1727 Anti-Beta-IV spectrin Antibody, clone N393/76
description whole antiserum	description affinity isolated antibody	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	description clone N393/76, from mouse
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form whole antiserum	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form purified immunoglobulin
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 100
biological source rabbit	biological source rabbit	biological source rabbit	biological source mouse
species reactivity human	species reactivity mouse, rabbit, dog, human, rat, bovine, pig, horse	species reactivity human	species reactivity human, rat
clone polyclonal	clone polyclonal	clone polyclonal	clone N393/76, monoclonal

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Storage Class

12 - Non Combustible Liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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Key Documents

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Anti-Spectrin antibody produced in rabbit

whole antiserum

Select a Size

About This Item

$443.00

biological source

Quality Segment

conjugate

antibody form

antibody product type

clone

contains

species reactivity

technique(s)

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Gene Information

General description

Immunogen

Application

Biochem/physiol Actions

Disclaimer

Compare Similar Items

This Item

Still not finding the right product?

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Flash Point (°F)

Flash Point (°C)

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Key Documents

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Anti-Spectrin antibody produced in rabbit

whole antiserum

Select a Size

About This Item

S1515-.2ML

$443.00

biological source

Quality Segment

conjugate

antibody form

antibody product type

clone

contains

species reactivity

technique(s)

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Gene Information

General description

Immunogen

Application

Biochem/physiol Actions

Disclaimer

Compare Similar Items

This Item

Still not finding the right product?

Safety Information

Storage Class

Flash Point (°F)

Flash Point (°C)

Documentation

Certificates of Analysis (COA)

Already Own This Product?

Product Citations

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Reviews

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