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S1515

Anti-Spectrin antibody produced in rabbit

whole antiserum

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0.2 mL
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$459.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00164739
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
16

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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

human

technique(s)

western blot: 1:400

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

General description

Spectrin is a multifunctional protein that has lipid-binding sites within CH (calponin-homology) tandem domains, a PH (pleckstrin homology) domain and triple helical segments. It is located on chromosome 1q23.1.
Spectrin is the major cytoskeletal component in erythrocytes. It is composed of two types of polypeptides known as α and β with molecular weights of 240 and 220 kDa, respectively. The α- and β-chains form heterotetramers which are linked end-to-end via oligomeric actin and band 4.1 protein.

Immunogen

spectrin from freshly prepared human erythrocyte ghosts.

Application

Anti-Spectrin antibody has been used in western blotting immunofluorescence and immunostaining.

Biochem/physiol Actions

Spectrins modulates the cell morphology and mechanical properties. Spectrins also participates in the cell cycle by controlling the upregulation of membrane receptors. α- and β spectrins are essential for the development of nervous system.
The antibody reacts specifically with the α and β chains of human erythrocyte spectrin.
The spectrin-based membrane skeleton is essential to provide mechanical stability and membrane integrity. It is also responsible for protein organization, trafficking and resilience of erythrocytes.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-Spectrin antibody produced in rabbit whole antiserum

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Sigma-Aldrich

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Anti-SPTB antibody produced in rabbit

description

whole antiserum

description

clone SB-SP1, ascites fluid

description

clone S393-2

description

Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

100

antibody form

whole antiserum

antibody form

ascites fluid

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

biological source

rabbit

biological source

mouse

biological source

mouse

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

shipped in

wet ice

clone

polyclonal

clone

SB-SP1, monoclonal

clone

S393-2, monoclonal

clone

polyclonal

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Storage Class

12 - Non Combustible Liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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