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Anti-STIM1 (N-terminal) antibody produced in rabbit

Name: Anti-STIM1 (N-terminal) antibody produced in rabbit
Brand: SIGMA
Price: 572 USD
Availability: InStock

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Enhanced Validation

Synonym(s):

STIM1 Antibody - Anti-STIM1 (N-terminal) antibody produced in rabbit, Stim1 Antibody, Anti-GOK, Anti-Stromal interaction molecule I

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Size/SKU	Availability	Price
100 μL	Check Cart for Availability	$572.00
200 μL	Check Cart for Availability	$712.00

About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IF, IP, WB

Citations:

$572.00

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 90 kDa

species reactivity

rat, mouse, human

enhanced validation

independent
Learn more about Antibody Enhanced Validation

concentration

~1 mg/mL

technique(s)

immunoprecipitation (IP): 2.5-5 μg using extracts of rat PC12 cells., indirect immunofluorescence: 5-10 μg/mL using human HeLa cells., western blot: 2-4 μg/mL using whole extract of mouse 3T3 cells.

UniProt accession no.

Q13586

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... STIM1(6786)
mouse ... Stim1(20866)
rat ... Stim1(117086)

Description

General description

STIM1 (stromal interaction molecule 1) is a conserved single-pass transmembrane protein, which is expressed ubiquitously in a wide variety of human primary and transformed cell types. STIM1 is modified by phosphorylation and N-linked glycosylation. STIM1 localized predominantly in the membrane of the endoplasmic reticulum (ER). It contains an N-terminal EF hand motif located in the ER lumen and appears to function as a sensor of ER Ca²⁺ levels.

Immunogen

synthetic peptide corresponding to amino acids 61-74 of human STIM1, conjugated to KLH via a C-terminal cysteine residue. The corresponding sequence is identical in rat and mouse.

Application

Anti-STIM1 (N-terminal) antibody produced in rabbit has been used in:

western blotting
immunoprecipitation
immunofluorescence

Biochem/physiol Actions

STIM1 (stromal interaction molecule 1) is required for the activation of store-operated Ca²⁺ influx. Overexpression of STIM1 and Orai1 markedly increases the calcium release-activated calcium (CRAC) current (I-CRAC).

Physical form

Solution in 0.01 M phosphate buffered saline, 7.4 pH, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	S6197	ZRB2043	HPA012123
Sigma-Aldrich S6072 Anti-STIM1 (N-terminal) antibody produced in rabbit	Sigma-Aldrich S6197 Anti-STIM1 (C-terminal) antibody produced in rabbit	ZRB2043 Anti-STIM1 Antibody, clone 2H7 ZooMAb^® Rabbit Monoclonal	Sigma-Aldrich HPA012123 Anti-STIM1 antibody produced in rabbit
description ~1 mg/mL, affinity isolated antibody, buffered aqueous solution	description ~1 mg/mL, affinity isolated antibody, buffered aqueous solution	description recombinant, expressed in HEK 293 cells	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form purified antibody	antibody form affinity isolated antibody
storage temp. −20°C	storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C
species reactivity rat, mouse, human	species reactivity human, rat, mouse	species reactivity mouse, human	species reactivity rat, human

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Storage Class

10 - Combustible liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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