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Anti-PKR antibody produced in rabbit

Name: Anti-PKR antibody produced in rabbit
Brand: SIGMA
Price: 605 USD

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-Interferon-inducible RNA-dependent protein kinase, Anti-Protein kinase RNA-activated

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Size/SKU	Availability	Price
100 μg	Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)	$605.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD03455796

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), IF, IHC, WB

Citations:

$605.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, mouse, rat

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

NCBI accession no.

AAP57628

UniProt accession no.

P19525

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... EIF2AK2(5610)

Description

General description

EIF2AK2 (eukaryotic translation initiation factor 2 α kinase 2) is an intracellular protein that is also called as RNA-dependent protein kinase (PKR). It belongs to the eIF2α family of protein kinases. The protein contains two RNA binding domains and a kinase domain. The PKR gene is localized on human chromosome 2p22-p21.

Immunogen

PKR antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human PKR.

Application

Anti-PKR antibody produced in rabbit has been used in Western Blotting.

Biochem/physiol Actions

EIF2AK2 (eukaryotic translation initiation factor 2 α kinase 2) plays a key role in antiviral responses promoted by interferons. It is involved in stress response and inflammation pathways. EIF2AK2 controls the development and multiplication of cells, nutrient signaling and metabolism. The protein also participates in several cell regulatory pathways like antiviral activity, growth suppression, transcriptional regulation and apoptosis.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500326.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	P0244	SAB4504639	ZRB1929
Sigma-Aldrich SAB3500326 Anti-PKR antibody produced in rabbit	$Anti-PKR (ET-20) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich P0244 Anti-PKR (ET-20) antibody produced in rabbit	Sigma-Aldrich SAB4504639 Anti-phospho-PKR (pThr²⁵⁸) antibody produced in rabbit	Sigma-Aldrich ZRB1929 Anti-PKR Antibody, clone 2H14 ZooMAb^® Rabbit Monoclonal
description affinity isolated antibody, buffered aqueous solution	description IgG fraction of antiserum, buffered aqueous solution	description affinity isolated antibody	description recombinant, expressed in HEK 293 cells
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 200
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form affinity isolated antibody	antibody form IgG fraction of antiserum	antibody form affinity isolated antibody	antibody form purified antibody
form buffered aqueous solution	form buffered aqueous solution	form buffered aqueous solution	form lyophilized
shipped in dry ice	shipped in dry ice	shipped in wet ice	shipped in ambient

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Storage Class

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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