Key Documents

View All Documentation

Anti-β-Tubulin III Antibody

Name: Anti-β-Tubulin III Antibody
Brand: SIGMA
Price: 192 USD
Availability: InStock

mouse monoclonal, SDL.3D10

Enhanced Validation

Synonym(s):

Anti-CDCBM, Anti-CDCBM1, Anti-CFEOM3, Anti-CFEOM3A, Anti-FEOM3, Anti-TUBB4, Anti-beta-4

Select a Size

Change View

Size/SKU	Availability	Price
25 μL	Available to ship onOctober 14, 2026fromMILWAUKEE	$192.00
100 μL	Available to ship onOctober 14, 2026fromMILWAUKEE	$572.00
0.2 mL	Available to ship onOctober 14, 2026fromMILWAUKEE	$760.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD01323870

Conjugate:

unconjugated

Clone:

SDL.3D10, monoclonal

Application:

ELISA (i), WB

Citations:

535

$192.00

Available to ship onOctober 14, 2026Details

Request a Custom Order

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Monoclonal Anti-β-Tubulin III antibody produced in mouse, clone SDL.3D10, ascites fluid

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

SDL.3D10, monoclonal

contains

15 mM sodium azide

species reactivity

bovine, rat, human, boar

packaging

antibody small pack of 25 μL

enhanced validation

knockout
Learn more about Antibody Enhanced Validation

technique(s)

indirect ELISA: suitable, western blot: 1:400 using a rat brain extract

isotype

IgG2b

UniProt accession no.

Q13509

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TUBB3(10381)
rat ... Tubb3(246118)

Description

General description

Monoclonal Anti-μ Tubulin Isotype III (mouse IgG2b isotype) is derived from the SDL.3D10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice.

Tubulin β 3 class III (TUBB3) also known as β-Tubulin III, is encoded by the gene mapped to human chromosome 16q24.3. TUBB3 protein expression is restricted to neurons.

Immunogen

synthetic peptide corresponding to the C-terminal sequence of human β-tubulin isotype III coupled to BSA

Application

It has also been used in immunofluorescence analysis.

Monoclonal Anti-β-Tubulin III antibody produced in mouse has been used in following studies:

Immunocytochemistry.
Flow cytometry.
Immunoblotting.

Biochem/physiol Actions

The antibody specifically recognizes an epitope located on isotype III of β-tubulin. No cross-reactivity with other tubulin isotypes is observed. The antibody can stimulate microtubule assembly when reconstituted with tubulin and either tau or MAP2.

Tubulin β 3 class III (TUBB3) plays a vital role in nervous system development and axon guidance. Mutation of the gene encoding protein leads to the ocular motility disorder, congenital fibrosis of the extraocular muscle type 3 (CFEOM3), and various neurological syndromes. Altered expression of the protein affects microtubule dynamics and microtubule-kinesin interactions. Increased expression of TUBB3 is observed in tumor tissues. Decreased expression of TUBB3 can be considered as an important marker for poor prognosis of cutaneous malignant melanoma. TUBB3 is implicated in the suppression of invasive growth of tumor tissue;therefore, it is considered to be a potential target for development of antitumor drugs.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	T5076	ZRB1140	T8578
Sigma-Aldrich T8660 Monoclonal Anti-β-Tubulin III antibody produced in mouse	Sigma-Aldrich T5076 Anti-β-Tubulin Isotype III antibody, Mouse monoclonal	Sigma-Aldrich ZRB1140 Anti-β-Tubulin III Antibody, clone 5H16, ZooMAb^® Rabbit Monoclonal	Sigma-Aldrich T8578 Anti-β-Tubulin III (neuronal) antibody, Mouse monoclonal
description clone SDL.3D10, ascites fluid	description clone SDL.3D10, purified from hybridoma cell culture	description recombinant, expressed in HEK 293 cells	description ~1.0 mg/mL, clone 2G10, purified from hybridoma cell culture
species reactivity bovine, rat, human, boar	species reactivity mouse, rat, human, boar, bovine	species reactivity human, mouse, rat	species reactivity human, mouse, rat
Gene Information human ... TUBB3(10381) rat ... Tubb3(246118)	Gene Information human ... TUBB3(10381) mouse ... Tubb3(22152) rat ... Tubb3(246118)	Gene Information human ... TUBB(203068)	Gene Information human ... TUBB3(10381) mouse ... Tubb3(22152) rat ... Tubb3(246118)
antibody form ascites fluid	antibody form purified immunoglobulin	antibody form purified antibody	antibody form purified from hybridoma cell culture
biological source mouse	biological source mouse	biological source rabbit (recombinant)	biological source mouse
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
clone SDL.3D10, monoclonal	clone SDL.3D10, monoclonal	clone 5H16, recombinant monoclonal	clone 2G10, monoclonal

Still not finding the right product?

Explore all of our products under Monoclonal Anti-β-Tubulin III antibody produced in mouse

— or —

Try our Product Selector Tool to narrow your options

Storage Class

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)