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Anti-VGLUT1 antibody produced in rabbit

Name: Anti-VGLUT1 antibody produced in rabbit
Brand: SIGMA
Price: 610 USD
Availability: InStock

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-BNPI, Anti-Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Anti-Vesicular Glutamate Transporter 1

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Size/SKU	Availability	Price
200 μL	Available to ship TODAYfromMILWAUKEE	$610.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.46

MDL number:

MFCD03792071

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ARR, WB CL

Citations:

$610.00

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 60 kDa

species reactivity

human

technique(s)

microarray: suitable, western blot (chemiluminescent): 1:1,000 using synaptic vesicle (SV) fraction of rat brain.

UniProt accession no.

Q9P2U7

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SLC17A7(57030)

Description

General description

VGLUT1 (vesicular glutamate transporter 1, originally termed BNPI and characterized as a Na⁺/Pi transporter) is a 60 kDa protein. VGLUT2 is enriched in synaptic vesicles and selective for a distinct class of glutaminergic nerve terminals.

Vesicular glutamate transporter 1 (VGLUT1), also called as solute carrier family 17 member 7 (SLC17A7), is encoded by the gene mapped to human chromosome 19q13, a region associated with schizophrenia. VGLUT1 is specifically expressed in neuronal cells in the brain and at higher levels in neuron-enriched regions such as the amygdala and hippocampus. Glia-enriched areas such as the corpus callosum also show moderate level of expression and substantia nigra, subthalamic nuclei and thalamus show low level expression. VGLUT1 is characterized with a conserved C-terminal dileucine-like motif and two polyproline domains distal to C- terminal end, including one that binds to endocytic BAR (Bin/Amphiphysin/Rvs) domain protein, endophilin.

Immunogen

synthetic peptide corresponding to a region near the C-terminus of human VGLUT1 (amino aicds 504-520).

Biochem/physiol Actions

Vesicular glutamate transporter 1 (VGLUT1) is associated with neuronal pathways that exhibit activity-dependent potentiation, whereas VGLUT2 is expressed in sensory and autonomic pathways that display high fidelity neurotransmission.

Vesicular glutamate transporter 1 (VGLUT1) plays a vital role as a vesicular glutamate transporter in glutamatergic neurons. VGLUT1 expression in the prefrontal cortex functions as a potential neurochemical marker of dementia in Alzheimer′s disease (AD) and antidepressant activity.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	HPA063679	HPA037856	HPA044839
$Anti-VGLUT1 antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich V0389 Anti-VGLUT1 antibody produced in rabbit	Sigma-Aldrich HPA063679 Anti-VGLUT1 antibody produced in rabbit	Sigma-Aldrich HPA037856 Anti-POGLUT1 antibody produced in rabbit	Sigma-Aldrich HPA044839 Anti-GLUD1 antibody produced in rabbit
description IgG fraction of antiserum, buffered aqueous solution	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
Quality Level 200	Quality Level 100	Quality Level -	Quality Level 100
antibody form IgG fraction of antiserum	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
Gene Information human ... SLC17A7(57030)	Gene Information human ... SLC17A7(57030)	Gene Information human ... POGLUT1(56983)	Gene Information human ... GLUD1(2746)
technique(s) microarray: suitable, western blot (chemiluminescent): 1:1,000 using synaptic vesicle (SV) fraction of rat brain.	technique(s) immunohistochemistry: 1:1000- 1:2500	technique(s) immunohistochemistry: 1:200-1:500, western blot: 0.04-0.4 μg/mL	technique(s) immunoblotting: 0.04-0.4 μg/mL, immunofluorescence: 0.25-2 μg/mL, immunohistochemistry: 1:1000-1:2500

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Storage Class

10 - Combustible liquids

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Anti-VGLUT1 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Select a Size

About This Item

$610.00

biological source

Quality Segment

conjugate

antibody form

antibody product type

clone

form

mol wt

species reactivity

technique(s)

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Gene Information

General description

Immunogen

Biochem/physiol Actions

Physical form

Disclaimer

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Anti-VGLUT1 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Select a Size

About This Item

V0389-200UL

$610.00

biological source

Quality Segment

conjugate

antibody form

antibody product type

clone

form

mol wt

species reactivity

technique(s)

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Gene Information

General description

Immunogen

Biochem/physiol Actions

Physical form

Disclaimer

Compare Similar Items

This Item

Still not finding the right product?

Safety Information

Storage Class

Documentation

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