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A0384

Arcaine sulfate salt

Synonym(s):

1,4-Diguanidinobutane sulfate salt

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Size/SKUAvailabilityPrice
50 mg
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$139.00

About This Item

Empirical Formula (Hill Notation):
C6H16N6 · H2O4S
CAS Number:
Molecular Weight:
270.31
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (TLC)
Form:
powder

$139.00


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biological source

synthetic (organic)

Quality Segment

assay

≥98% (TLC)

form

powder

mp

>280 °C

solubility

1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES string

OS(O)(=O)=O.NC(=N)NCCCCNC(N)=N

InChI

1S/C6H16N6.H2O4S/c7-5(8)11-3-1-2-4-12-6(9)10;1-5(2,3)4/h1-4H2,(H4,7,8,11)(H4,9,10,12);(H2,1,2,3,4)

InChI key

RWTGFMPOODRXIM-UHFFFAOYSA-N

Application

Arcaine sulfate salt has been used as an N-methyl-d-aspartate (NMDA) receptor effector/antagonist:
  • to evaluate its effects on the acquisition of electrical kindling of the amygdala
  • to compare its effects with agmatine and MK801 on NMDA- or glutamate-induced neuronal damage
  • to study its effects on cell-free translation of synthetic polynucleotide

Biochem/physiol Actions

Arcaine sulfate salt (1,4-diguanidinobutane), a polyamine, is an antagonist of the polyamine binding site of the N-methyl-d-aspartate (NMDA) receptor. Arcaine, an agmatine analog, along with ifenprodil, might have a possibility for therapeutic management in epileptic disorders.

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description

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description

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description

≥93% (TLC), powder

description

xanthine oxidase inhibitor

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥93% (TLC)

assay

≥99% (TLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

200

Quality Level

100

Quality Level

-

Quality Level

200

solubility

1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

methanol: 50 mg/mL, clear, colorless to faint yellow or tan

solubility

methanol: soluble, clear to hazy

solubility

1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

mp

>280 °C

mp

283-285  °C

mp

148-149 °C (dec.) (lit.)

mp

>300 °C (lit.)

Gene Information

human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)

Gene Information

human ... PTGS1(5742), PTGS2(5743)

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

Gene Information

human ... XDH(7498)


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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