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A0384

Arcaine sulfate salt

Synonym(s):

1,4-Diguanidinobutane sulfate salt

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Size/SKUAvailabilityPrice
50 mg

Available to ship TODAY

$144.00

About This Item

Empirical Formula (Hill Notation):
C6H16N6 · H2O4S
CAS Number:
Molecular Weight:
270.31
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (TLC)
Form:
powder

$144.00


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biological source

synthetic (organic)

Quality Segment

assay

≥98% (TLC)

form

powder

mp

>280 °C

solubility

1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES string

OS(O)(=O)=O.NC(=N)NCCCCNC(N)=N

InChI

1S/C6H16N6.H2O4S/c7-5(8)11-3-1-2-4-12-6(9)10;1-5(2,3)4/h1-4H2,(H4,7,8,11)(H4,9,10,12);(H2,1,2,3,4)

InChI key

RWTGFMPOODRXIM-UHFFFAOYSA-N

Application

Arcaine sulfate salt has been used as an N-methyl-d-aspartate (NMDA) receptor effector/antagonist:
  • to evaluate its effects on the acquisition of electrical kindling of the amygdala
  • to compare its effects with agmatine and MK801 on NMDA- or glutamate-induced neuronal damage
  • to study its effects on cell-free translation of synthetic polynucleotide

Biochem/physiol Actions

Arcaine sulfate salt (1,4-diguanidinobutane), a polyamine, is an antagonist of the polyamine binding site of the N-methyl-d-aspartate (NMDA) receptor. Arcaine, an agmatine analog, along with ifenprodil, might have a possibility for therapeutic management in epileptic disorders.

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This Item
SML1025PHR1252
description

-

description

≥98% (HPLC)

description

Pharmaceutical Secondary Standard; Certified Reference Material

form

powder

form

powder

form

-

assay

≥98% (TLC)

assay

≥98% (HPLC)

assay

-

Quality Level

200

Quality Level

100

Quality Level

300

solubility

1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

H2O: 10 mg/mL, clear

solubility

-

mp

>280 °C

mp

-

mp

167-169 °C (lit.)

Gene Information

human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)

Gene Information

-

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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