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A0608

ABL1 (27-end), active, His-tagged from mouse

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

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Synonym(s):

JTK7, c-ABL, p150, v-abl

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10 μg
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$490.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
Specific activity:
717-971 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells

$490.00

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recombinant

expressed in baculovirus infected Sf9 cells

Quality Segment

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

717-971 nmol/min·mg

mol wt

~135 kDa

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

mouse ... Abl1(11350)

Biochem/physiol Actions

ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of ABL protein is negatively regulated by its SH3 domain and deletion of the SH3 domain turns ABL1 into an oncogene. Translocation and head-to-tail fusion of the BCR and ABL1 genes is present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDK1-mediated phosphorylation, suggesting a cell cycle function for ABL1.

Physical form

Supplied in 50mM NaPhosphate pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1mM PMSF, 0.2 mM DTT, 25% glycerol

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
SRP5279HPA028409SAB4501044
description

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

description

PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

description

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

description

affinity isolated antibody

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

-

assay

-

specific activity

717-971 nmol/min·mg

specific activity

663-1024 nmol/min·mg

specific activity

-

specific activity

-

Gene Information

mouse ... Abl1(11350)

Gene Information

human ... ABL1(25)

Gene Information

human ... ABL1(25)

Gene Information

human ... ABL1(25)

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous solution

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

-

recombinant

-

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−20°C

storage temp.

−20°C


Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Codes

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)



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