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Azaserine

Name: Azaserine
Brand: SIGMA
Price: 54.5 USD
Availability: InStock

Hybri-Max^™, γ-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma

Synonym(s):

O-Diazoacetyl-L-serine

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Size/SKU	Availability	Price
0.5 mg	Check Cart for Availability	$54.50

About This Item

Empirical Formula (Hill Notation):

C₅H₇N₃O₄

CAS Number:

115-02-6

Molecular Weight:

173.13

UNSPSC Code:

12352207

NACRES:

NA.75

PubChem Substance ID:

24890511

EC Number:

204-061-6

Beilstein/REAXYS Number:

1726602

MDL number:

MFCD00036802

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Properties

grade

Hybri-Max^™

Quality Segment

200

sterility

γ-irradiated

product line

BioXtra

form

lyophilized powder

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

antibiotic activity spectrum

fungi

mode of action

enzyme | inhibits

storage temp.

−20°C

SMILES string

N[C@@H](COC(=O)C=[N+]=[N-])C(O)=O

InChI

1S/C5H7N3O4/c6-3(5(10)11)2-12-4(9)1-8-7/h1,3H,2,6H2,(H,10,11)/t3-/m0/s1

InChI key

MZZGOOYMKKIOOX-VKHMYHEASA-N

Description

General description

Chemical structure: amino acid derivatives

Application

For use in hybridoma cell culture applications as a myeloma selection agent. Used to study inhibition of formylglycinamide ribonucleotide amidotransferase and PRPP amidotransferase.

Biochem/physiol Actions

Azaserine is an antibiotic, generated by Streptomyces fragilis. It is considered as a potential mutation inducing agent. It is known to promote pancreatic cancer and induces adenoma and carcinoma in vivo and in vitro. Azaserine also stimulates kidney and liver tumors in rats.

Preparation Note

Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500 mL medium. Final working concentration: 5.7 μM azaserine.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

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This Item	A4142	A7422	A5539
Sigma-Aldrich A1164 Azaserine	Sigma-Aldrich A4142 Azaserine	Sigma-Aldrich A7422 AT Media Supplement (50×) Hybri-Max^™	Sigma-Aldrich A5539 AAT Media Supplement (50×) Hybri-Max^™
description Hybri-Max^™, γ-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma	description ≥98% (TLC)	description γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma	description γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma
technique(s) cell culture \| hybridoma: suitable	technique(s) -	technique(s) cell culture \| hybridoma: suitable	technique(s) cell culture \| hybridoma: suitable
form lyophilized powder	form powder	form lyophilized powder	form lyophilized powder
sterility γ-irradiated	sterility -	sterility γ-irradiated	sterility γ-irradiated
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
grade Hybri-Max^™	grade -	grade -	grade -
impurities endotoxin, tested	impurities -	impurities endotoxin, tested	impurities endotoxin, tested

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Pictograms

GHS06,GHS08

Signal Word

Danger

Hazard Codes

H301,H351

Precautionary Statements

P201 - P301 + P310 + P330

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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