Skip to Content
MilliporeSigma

Skip To

A1221

AH6809

≥98%, crystalline solid or supercooled liquid

Synonym(s):

6-Isopropoxy-9-oxoxanthene-2-carboxylic acid

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mg
Check Cart for Availability
$87.55

About This Item

Empirical Formula (Hill Notation):
C17H14O5
CAS Number:
Molecular Weight:
298.29
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98%
Form:
crystalline solid or supercooled liquid

$87.55

List Price$103.00Save 15%

Check Cart for Availability

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Segment

assay

≥98%

form

crystalline solid or supercooled liquid

solubility

ethanol: soluble 2.5 mg/mL, DMSO or DMF: soluble 8 mg/mL

SMILES string

CC(C)Oc1ccc2c(Oc3ccc(cc3C2=O)C(O)=O)c1

InChI

1S/C17H14O5/c1-9(2)21-11-4-5-12-15(8-11)22-14-6-3-10(17(19)20)7-13(14)16(12)18/h3-9H,1-2H3,(H,19,20)

InChI key

AQFFXPQJLZFABJ-UHFFFAOYSA-N

Application

AH6809 has been used:
  • as a prostaglandin E2 receptor 1 & 2 (EP1/2) antagonist to analyze its effects on cyclooxygenase-2 /prostaglandin E2 (COX-2/PGE2) signaling in the angiogenic feedback of endothelial cells to hypoxia[1]
  • as an EP2 antagonist to study its effects on tumor angiogenesis in human prostate cancer cell lines[2]
  • as an EP2 antagonist to analyze its effects on overexpression of amyloid precursor protein (APP)[3]

Biochem/physiol Actions

AH6809 plays a role in antagonizing the proliferation of non-small cell lung cancer cell lines.[4]
DP/EP prostanoid receptor antagonist; has the highest affinity for DP receptors, but also acts as a weak antagonist at murine EP1 and EP2 prostanoid receptors.

Features and Benefits

This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
C5865S3065C0496
description

≥98%, crystalline solid or supercooled liquid

description

≥98% (HPLC), solid

description

≥98% (HPLC), solid

description

≥98% (HPLC)

form

crystalline solid or supercooled liquid

form

solid

form

solid

form

powder

assay

≥98%

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

ethanol: soluble 2.5 mg/mL, DMSO or DMF: soluble 8 mg/mL

solubility

DMSO: >10 mg/mL, H2O: insoluble

solubility

DMSO: soluble 10 mg/mL, H2O: insoluble

solubility

DMSO: >20 mg/mL


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Questions

Reviews

No rating value

Active Filters