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A138

Aminobenztropine

solid

Synonym(s):

3-(2′-Aminobenzhydryloxy)tropane, ABT

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50 mg
5 left in stock
$234.00
$198.90

About This Item

Empirical Formula (Hill Notation):
C21H26N2O
CAS Number:
88097-86-3
Molecular Weight:
322.44
NACRES:
NA.77
PubChem Substance ID:
24277819
UNSPSC Code:
12352200
MDL number:
MFCD00078565
Form:
solid
Quality level:
100

$198.90

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form

solid

Quality Level

100

color

white

solubility

0.1 M HCl: soluble, 0.1 M NaOH: insoluble, DMSO: soluble, methanol: soluble

SMILES string

CN1C2CCC1CC(C2)OC(c3ccccc3)c4ccccc4N

InChI

1S/C21H26N2O/c1-23-16-11-12-17(23)14-18(13-16)24-21(15-7-3-2-4-8-15)19-9-5-6-10-20(19)22/h2-10,16-18,21H,11-14,22H2,1H3

InChI key

KZFDKINRISJFCO-UHFFFAOYSA-N

Gene Information

human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

Biochem/physiol Actions

High affinity muscarinic ligand that has been used for affinity purification of muscarinic cholinergic receptors.

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This Item
A143T4182D122
Aminobenztropine solid

Sigma-Aldrich

A138

Aminobenztropine

(S)-(−)-Atenolol powder

Sigma-Aldrich

A143

(S)-(−)-Atenolol

Tyrphostin AG 1478 ≥98%

Sigma-Aldrich

T4182

Tyrphostin AG 1478

Domperidone powder, ≥98% (HPLC)

Sigma-Aldrich

D122

Domperidone

form

solid

form

powder

form

solid

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

0.1 M HCl: soluble, DMSO: soluble, methanol: soluble, 0.1 M NaOH: insoluble

solubility

0.1 M HCl: soluble

solubility

0.1 M HCl: soluble <0.4 mg/mL, DMSO:methanol (1:1): soluble 10 mg/mL, clear, colorless, ethanol: soluble 10 mg/mL, methylene chloride: soluble 10 mg/mL, 0.1 M NaOH: insoluble, 2-hydroxypropyl-β-cyclodextrin: insoluble, H2O: insoluble

solubility

DMSO: >10 mg/mL, 0.1 M HCl: soluble, 0.1 M NaOH: slightly soluble, H2O: insoluble

color

white

color

white to beige

color

-

color

white

Gene Information

human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

Gene Information

human ... ADRB1(153)

Gene Information

human ... EGFR(1956)
mouse ... Egfr(13649)

Gene Information

human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), KCNH2(3757)
rat ... Drd1a(24316), Drd2(24318), Drd3(29238), Htr3a(79246)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
098K4618
038K4624
076K4619
125K4607

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Although the pathophysiology of carbamazepine-induced idiosyncratic or hypersensitivity reactions is unclear, they are presumed to be immune mediated, involving a complex interaction between drug metabolism and activation of the immune system. Cell stress can be caused by reactive metabolites, and
Takafumi Tomida et al.
The Journal of toxicological sciences, 42(5), 641-650 (2017-09-15)
The utility of HepaRG cells as an in vitro cell-based assay system for predicting drug-induced phospholipidosis (PLD) was investigated. In experiment 1, 10 PLD-positive compounds and 11 PLD-negative compounds were selected. HepaRG cells were treated with each compound for 48
K Haga et al.
The Journal of biological chemistry, 258(22), 13575-13579 (1983-11-25)
A novel compound, 3-(2'-aminobenzhydryloxy)-tropane (ABT), and an ABT-agarose gel were synthesized and used for the purification of solubilized muscarinic receptors. ABT had a high affinity with an apparent dissociation constant (Kd) of 7 nM for the muscarinic receptors solubilized from
View All Related Papers

Global Trade Item Number

SKUGTIN
A138-250MG04061832079103
A138-50MG04061832088563

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