Key Documents

View All Documentation

Anti-Activin A antibody produced in goat

Name: Anti-Activin A antibody produced in goat
Brand: SIGMA
Price: 628 USD
Availability: InStock

affinity isolated antibody, lyophilized powder

Synonym(s):

Activin A Antibody, Anti-Activin A antibody produced in goat

Select a Size

Change View

Size/SKU	Availability	Price
0.1 mg	Available to ship TODAYfromMILWAUKEE	$628.00

About This Item

UNSPSC Code:

51111800

NACRES:

NA.41

MDL number:

MFCD02095789

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA, IHC (p), Neutral, WB

Citations:

$628.00

Available to ship TODAYDetails

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

goat

Quality Segment

100

recombinant

expressed in goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

ELISA: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5-15 μg/mL, neutralization: suitable, western blot: 0.1 μg/mL

UniProt accession no.

P08476

application(s)

research pathology

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... INHBA(3624)

Description

General description

Activin A protein belongs to the transforming growth factor-β (TGF-β) superfamily. This protein is a homodimer of two βA subunits. The INHBA gene is located on the human chromosome at 7p14.1.

Immunogen

recombinant human activin A expressed in CHO cells.

Application

Anti-Activin A antibody can be used for immunohistochemistry (5-15 μg/mL), western blot (0.1 μg/mL) and neutralization assays.

Anti-Activin A antibody produced in goat has been used in immunohistochemical staining.

Biochem/physiol Actions

Activin A protein is involved in regulating developmental genes such as cell cycle regulators like p21, p15, paired box protein (Pax-6) and hormones like follicle-stimulating hormone (FSH). This protein also regulates its antagonist like follistatin and mothers against decapentaplegic homolog 7 (SMAD7). Activin A protein binds to the type 1 receptor activin receptor type 1B (ActR1B) and type 2 receptor activin receptor 2A and 2B (ActRIIA and ActRIIB). Activin A gene is highly expressed in esophageal carcinoma, lung adenocarcinoma, and malignant pleural mesothelioma (MPM). This gene expression is decreased during breast cancer, neuroblastoma, and hepatocellular carcinoma (HCC). Activins bind to the type II Activin receptor triggering phosphorylation of type I Activin receptor (ALK4) and activation of downstream pathways such as proliferation and apoptosis. Activin acts as a tumor suppressor by reducing cell proliferation in cancer cells.

Physical form

Lyophilized from 0.2 μm-filtered solution in phosphate buffered saline containing carbohydrates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	AMAB92029	SAB1408593	SAB5702464
Sigma-Aldrich A1594 Anti-Activin A antibody produced in goat	AMAB92029 Monoclonal Anti-INHBA antibody produced in mouse	Sigma-Aldrich SAB1408593 Anti-INHBA antibody produced in rabbit	Sigma-Aldrich SAB5702464 Anti-Inhibin beta A (INHBA) Antibody, clone 1X6N9, Rabbit Monoclonal
description affinity isolated antibody, lyophilized powder	description Prestige Antibodies^® Powered by Atlas Antibodies, clone CL15357, purified antibody (Protein A)	description purified immunoglobulin, buffered aqueous solution	description -
biological source goat	biological source mouse	biological source rabbit	biological source rabbit
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form affinity isolated antibody	antibody form purified antibody (Protein A)	antibody form purified immunoglobulin	antibody form -
form lyophilized powder	form -	form buffered aqueous solution	form liquid
storage temp. −20°C	storage temp. -10 to -25°C	storage temp. −20°C	storage temp. −20°C

Still not finding the right product?

Try our Product Selector Tool to narrow your options

Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.